首页> 外文期刊>Inorganic Chemistry Communications >Synthesis and characterization of new biologically active palladium(II) complexes with (1E,6E)-1,7-bis(3,4-diethoxyphenyl)-1,6-heptadiene-3,5-dione
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Synthesis and characterization of new biologically active palladium(II) complexes with (1E,6E)-1,7-bis(3,4-diethoxyphenyl)-1,6-heptadiene-3,5-dione

机译:具有(1E,6E)-1,7-双(3,4-二乙氧基苯基)-1,6-庚二烯-3,5-二酮的新型生物活性钯(II)配合物的合成与表征

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摘要

Two new palladium complexes with (1E,6E)-1,7-bis(3,4-diethoxyphenyl)-1,6-heptadiene-3,5-dione, 1 and 2, have been synthesized and structurally characterized. Complex 1 has the molecular structure confirmed by X-ray diffraction measurements. Both complexes display a significant antiproliferative activity against human colorectal cancer cells by inducing early and late apoptotic processes in those cells.
机译:合成了两种新的具有(1E,6E)-1,7-双(3,4-二乙氧基苯基)-1,6-庚二烯-3,5-二酮1和2的钯配合物,并对其结构进行了表征。配合物1具有通过X射线衍射测量证实的分子结构。两种复合物均通过诱导早期和晚期细胞凋亡过程而对人结肠直肠癌细胞显示出显着的抗增殖活性。

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