SYNTHESIS AND EVALUATION OF SOME NOVEL 2-(4-METHOXYPHENYL)-4, ?-DIPHENYL-1,3-THIAZQLE AND 2-(4-HYDROXYPHENYL)-4,5-DIPHENYL-1, 3-TRIAZOLE FOR ANTI-TUBERCULAR AND ANTI-MICROBIAL ACTIVITIES

摘要

A series of 2-(4-methoxypheny!)-4,5-diphenyl-1,3-thiazole, and 2-(4-hydroxyphenyl)-4,5-diphenyl-1,3-triazole derivatives have been synthesised and evaluated for antibacterial, antifungal and antitubercular activities. The newly synthesised compounds have been characterized by IR, ~1H-NMR and CHN analysis. All the compounds have shown promising antibacterial, antifungal and antitubercular activities when compared with standard drug ciprofloxacin, griseofulvin and streptomycin respectively.