"The role of osteopontin in milk is elusive. It is yet to be established if osteopontin or peptides derived from it are absorbed from the gastrointestinal tract, and if so, whether they retain their biological activity and are transported to possiblesites for action within the body." Milk proteins are a heterogenous group of proteins providing essential amino acids for nutritional purposes of humans and animals. Recent advances have shown milk proteins to be more complex with exhibiting additional biofunctional protein molecules having considerable physiological significance for neonatal growth and development by protecting against disease and infection. Osteopontin is one such multi-biofunctional minor milk protein in addition to lactoferrin, lactoperoxidase, immunoglobulins, mucin-1, secretory component, lysozyme, lactadherin, lactophorin and several other milk protein induced bioactives.
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