Toxic Effect of Nanoparticles of Metals (Pb, Cd, Ag, Mn, Fe and Zn) and Metal Oxides (ZnO, CuO, TiO2 and CeO2) in Human Body.

摘要

Nanoparticle production and usage are one necessity of various industrial fields in recent years. The environmental effect and effect in human body are the major concern, but possibility of unnoticed. These particles affect the animal cell and create too many comprehensive effects. Metals and metal oxides are the two groups of nanoparticles with large scale application, various preparations of these nano particles are commonly available, but effects of these particles are less discussed. This study tried to reveals those effects of various nanoparticles with particle size (diameter, length and agglomeration), duration of the treatment, and type of cells. Cytotoxic effects have also been reported, but the toxicological data specific to nanoparticles due to the small number of studies. Absorption, translocation to other tissues or organs, biopersistence, carcinogenicity etc with risk associated factors were the major studies conducted. The nanoparticles are harmful only when they get inside and also depend on the particle size, time of contact and nature of cell which is contacted.