New substituted m-Phenoxy chakomes; their synthesis by microwave irradiation and antifungal activity

摘要

Chalcones represent a group of compounds with interesting biological activities that are formed from a Claisen-Schmidt condensation between a aromatic benzaldehyde and an acetophenones in the presence of sodium hydroxide NaOH as a catalyst. A m-phenoxy benzaldehyde reacted with substituted aromatic acetophenones in presence of base to formed chalcones. The structures of all the synthesized compounds have been confirmed by elemental analysis and spectral data. The synthesized compounds have been tested for their antifungal activity.