Application of Autogenous Venous Nerve Conduits for Digital Nerve Reconstruction

摘要

The use of an autogenous tube to reconstruct a gap in a nerve has been described by many authors in the last 150 years. Various structures have been used to provide a tube, including decalcified bone (Gluck [1]), brachial artery (Bungnar [2]), and vein (Foramitti [3] and Nageotte [4]), but little success was obtained, and these procedures were abandoned. There were many more unsuccessful reports of biologic tubes used for nerve reconstruction during the first half of the twentieth century. Chiu et al [5-7] revisited this previous work in the animal model and subsequently in humans. Their work showed good,histologic and clinical evidence of nerve regeneration across a gap in a nerve bridged by an autogenous vein. The autogenous venous nerve conduit (AVNC) works in conjunction with the influence of various nerve factors to allow the preferential growth of a nerve down a hollow biologic conduit [8].