Targeting management of fever, hyperglycemia, and swallowing improved outcomes in acute stroke

摘要

Does an intervention targeting management of fever, hyper-glycemia, and swallowing dysfunction (FeSS) after acute stroke improve patient outcomes more than access to existing guidelines? Methods Design: Cluster randomized controlled trial (Quality in Acute Stroke Care [QASC] study). Australia New Zealand Clinical Trial Registry ACTRN12608000563369. Allocation: Concealed. Blinding: Blinded (patients, research assistants, and statistician).Follow-up period: 90 days after hospital admission.Setting: 19 acute stroke units (ASUs) in New South Wales, Australia.Patients: 1126 English-speaking patients > 18 years of age (70% > 65 y, 60% men) who had ischemic stroke or intracerebral hemorrhage and presented < 48 hours after symptom onset. Exclusion criteria included admission for palliative care.