In February 2013, a 70-year-old woman was diagnosed with acute myeloid leukaemia (AML). Blood counts at first diagnosis were leucocytes 32l, thrombocytes 42l and haemoglobin 9.5 g/dl. Bone marrow showed 80 % myeloid blasts; cytogenetic testing revealed a female karyotype with trisomy 11. Thereafter, cytoreductive oral chemotherapy with hydroxycarbamide was initiated followed by a 7-day cycle of cytarabine 100 mg/m2/24 h (day 1-day 7) and daunorubicin 60 mg/m2/3 h (day 3-day 5). At the end of chemotherapy, the patient collapsed at night and sustained an acromioclavicular separation, which could not be treated due to her thrombocytopenia. Moreover, the patient's mental condition aggravated: starting with lowering vigilance, she presented complete disorientation, intermittent agitation and aggression in clear moments.
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