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Design and optimization of a beam shaping assembly for BNCT based on D-T neutron generator and dose evaluation using a simulated head phantom

机译:基于D-T中子发生器的BNCT束整形组件的设计和优化,以及使用模拟的头部模型进行剂量评估

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摘要

A feasibility study was conducted to design a beam shaping assembly for BNCT based on D-T neutron generator. The optimization of this configuration has been realized in different steps. This proposed system consists of metallic uranium as neutron multiplier, TiF 3 and Al 2O 3 as moderators, Pb as reflector, Ni as shield and Li-Poly as collimator to guide neutrons toward the patient position. The in-air parameters recommended by IAEA were assessed for this proposed configuration without using any filters which enables us to have a high epithermal neutron flux at the beam port. Also a simulated Snyder head phantom was used to evaluate dose profiles due to the irradiation of designed beam. The dose evaluation results and depth-dose curves show that the neutron beam designed in this work is effective for deep-seated brain tumor treatments even with D-T neutron generator with a neutron yield of 2.4×10 12n/s. The Monte Carlo Code MCNP-4C is used in order to perform these calculations.
机译:进行了可行性研究,以设计基于D-T中子发生器的BNCT束整形组件。此配置的优化已通过不同的步骤实现。该提议的系统由金属铀作为中子倍增器,TiF 3和Al 2O 3作为缓和剂,Pb作为反射器,Ni作为屏蔽层和Li-Poly作为准直仪将中子引向患者位置。在不使用任何过滤器的情况下,针对此拟议配置评估了国际原子能机构推荐的空中参数,这使我们能够在束口处获得高的超热中子通量。由于设计光束的照射,模拟的Snyder头部幻影也用于评估剂量分布。剂量评估结果和深度剂量曲线表明,即使使用D-T中子发生器,中子产量为2.4×10 12n / s,这项工作设计的中子束也能有效治疗深部脑肿瘤。为了执行这些计算,使用了蒙特卡罗代码MCNP-4C。

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