Developing venous gangrene in deep vein thrombosis: intraarterial low-dose burst therapy with urokinase--case reports.

摘要

Two patients with developing venous gangrene of the lower extremity and contraindications to systemic thrombolytic therapy are presented. Low-dose intraarterial burst therapy with urokinase provided rapid amelioration of symptoms and avoided amputation without any serious bleeding complications in both patients.