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Ensuring Reproducibly Accurate Drug Dilution Protocols

机译:确保可重复准确的药物稀释方案

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摘要

Respiratory drug discovery and development specialists, Pulmocide Ltd, are using an Integra VIAFLO Assist pipetting assistant to enhance the productivity and reproducibility of their screening of novel compounds in a range of biological assays. Pulmocide is generating a pipeline of potent anti-infective agents for delivery by inhaled administration for the treatment of life threatening lower respiratory tract viral and fungal infections specifically RSV pneumonia and Invasive Aspergillosis. The lung is the principle site of infection for RSV and Aspergillus and delivery of highly effective new treatments directly to the lung will allow rapid control of infection with minimal systemic toxicity. Lauren Anderson Dring, Research Scientist and Project Manager at Pulmocide commented: "Our work involves medium throughput screening of novel compounds in a range of biological assays. This involves accurate drug dilutions which ultimately allow us to analysis each compound's potency; thus aiding the rapid discovery of highly effective new treatments for respiratory tract infections.
机译:呼吸药物发现和开发专家Pulmocide Ltd正在使用Integra Viaflo Assiss移液助手来提高其在一系列生物学测定中筛选新化合物的生产率和可重复性。 Pulmocide正在生成一条有效的抗感染剂管道,用于通过吸入施用,以治疗威胁下呼吸道病毒和真菌感染的生命,特异性RSV肺炎和浸润性曲霉病。肺是RSV和曲霉感染的主要部位,直接向肺部递送高效的新疗法将允许以最小的全身毒性来快速控制感染。 Pulmocide的研究科学家兼项目经理Lauren Anderson Dring评论说:“我们的工作涉及一系列生物学测定中新型化合物的中等吞吐量筛查。这涉及准确的药物稀释液,最终使我们能够分析每种化合物的效力;因此,快速发现了迅速的发现;高效的呼吸道感染的新疗法。

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