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首页> 外文期刊>Annals of Biomedical Engineering: The Journal of the Biomedical Engineering Society >Assessing the use of the 'opening angle method' to enforce residual stresses in patient-specific arteries.
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Assessing the use of the 'opening angle method' to enforce residual stresses in patient-specific arteries.

机译:评估“开角法”的使用以在患者特定的动脉中施加残余应力。

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Numerical and analytical studies on cylindrical geometries have shown the relevance of accounting for residual stresses in arterial modeling. However, multiple difficulties, both geometrical and numerical, arise when enforcing residual stresses in patient-specific arteries. This is the reason of the few simulations that have been developed on this kind of geometries. In this paper we present a methodology that allows to include residual stresses in arbitrary geometries. Since it is not necessary to know the opened configuration of the artery, it makes it possible to take advantage of non-invasive image acquisition techniques such as CT or MRI to create customized arterial models. A simplified initial strain field showing its accuracy when applied to actual in vivo closed geometries is hypothesized from an opening angle experiment. In addition to residual stresses, the anisotropic hyperelastic and multilayered nature of the arterial tissue was accounted for the simulations of the behavior of a human coronary and iliac arteries. Results show the relevance of considering all these features for getting realistic results and the relative accuracy of using approximate solutions of residual stresses in patient-specific arterial simulations.
机译:对圆柱几何形状的数值和分析研究表明,在动脉建模中考虑残余应力的相关性。但是,在患者特定的动脉中施加残余应力时,会出现几何和数值方面的多重困难。这是针对这种几何形状进行的少数模拟的原因。在本文中,我们提出了一种允许在任意几何形状中包括残余应力的方法。由于不必知道动脉的打开形态,因此可以利用非侵入性图像采集技术(例如CT或MRI)来创建自定义的动脉模型。从开角实验中假设了一个简化的初始应变场,该场显示了其应用于实际体内闭合几何形状时的精度。除了残余应力外,动脉组织的各向异性超弹性和多层性质还用于模拟人类冠状动脉和动脉的行为。结果表明,考虑所有这些特征以获取实际结果以及在特定于患者的动脉模拟中使用残余应力的近似解的相对准确性具有相关性。

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