Optimizing Tuberculosis Diagnosis in Human Immunodeficiency Virus–Infected Inpatients Meeting the Criteria of Seriously Ill in the World Health Organization Algorithm

摘要

We assessed the World Health Organization algorithm for diagnosing tuberculosis in seriously ill Human Immunodeficiency Virus-infected inpatients and developed a clinical prediction rule with good diagnostic utility. The Xpert MTB/RIF assay showed high sensitivity, especially when performed on induced rather than spontaneously expectorated sputum.