Fuzzy Decision of Drug Dosage for Type-1 Human Immunodeficiency Virus Infected Patients

摘要

The research subject of fuzzy decision of drug dosage for type-1 human immunodeficiency virus(HIV-1) infected patients is discussed by the aid of a existing fuzzy dynamic HIV-1 model. Firstly, by making use of the previous fuzzy modeling method, that intractable nonlinear predator-prey like model is converted to a set of tractable linear sub-models. Then, based on the above tractable sub-models and a kind of sampled-data fuzzy control strategy with a set of decay factors, all the dynamic properties of the fuzzy dynamic HIV-1 model can be acquired by means of high-performance computer simulations. Thirdly, some fuzzy decisions of drug dosage for HIV-1 infected patients are reasoned by consulting the computer simulation results and thus a bank of instructional advices are suggested for clinic care. Finally, some conclusions and future study directions are specifically discussed in the conclusion part.