OUR ever-increasing knowledge of the human genome has revealed the genetic basis underlying many diseases while simultaneously providing us with a greater understanding of normal intraspecies genetic variability. This raises the possibility that, as 21st century physicians, we will be able to practice a personalized form of medicine specifically tailored to the genetic makeup of each patient. One key question for anesthesiology is how clinically relevant is genetic diversity in the day-to-day practice of anesthesia.
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