机译:激活P53家族成员TAP63:一种靶向P53改变肿瘤的新型治疗策略
Department of Biochemistry and BiologyUniversity of HoustonHouston Texas;
Department of Biochemistry and BiologyUniversity of HoustonHouston Texas;
Department of Oncology Lombardi Comprehensive Cancer CenterGeorgetown UniversityWashington;
Department of Molecular and Cellular Oncology Division of Basic ScienceThe University of Texas MD;
Lester and Sue Smith Breast CenterBaylor College of MedicineHouston Texas;
Department of Molecular and Cellular Oncology Division of Basic ScienceThe University of Texas MD;
Department of Oncology Lombardi Comprehensive Cancer CenterGeorgetown UniversityWashington;
Department of Molecular and Cellular Oncology Division of Basic ScienceThe University of Texas MD;
Department of Biochemistry and BiologyUniversity of HoustonHouston Texas;
SynerGene Therapeutics Inc.Potomac Maryland;
Department of Oncology Lombardi Comprehensive Cancer CenterGeorgetown UniversityWashington;
Department of Molecular and Cell BiologyBaylor College of MedicineHouston Texas;
Department of Integrative Biology and PhysiologyUniversity of CaliforniaLos Angeles California;
Gynecologic Oncology and Reproductive MedicineThe University of Texas MD Anderson Cancer;
Center for RNAi and Non-Coding RNAsThe University of Texas MD Anderson Cancer CenterHouston Texas;
Gynecologic Oncology and Reproductive MedicineThe University of Texas MD Anderson Cancer;
Department of Integrative Biology and PhysiologyUniversity of CaliforniaLos Angeles California;
Department of Molecular and Cell BiologyBaylor College of MedicineHouston Texas;
Department of Oncology Lombardi Comprehensive Cancer CenterGeorgetown UniversityWashington;
Department of Molecular and Cellular Oncology Division of Basic ScienceThe University of Texas MD;
Department of Oncology Lombardi Comprehensive Cancer CenterGeorgetown UniversityWashington;
3‐dimensional (3D) spheroids; B‐cell lymphoma 2‐like protein 11 ( BIM ); chemosensitization; cisplatin; leoyl‐sn‐glycero‐3‐phosphatidylcholine (DOPC); microRNA 130b (miR‐130b); ovarian cancer; transactivation (TA) and N‐terminally truncated (ΔN) isoforms of the p63 protein ( TAp63/ΔNp63 ); tumor protein p53; tumor‐targeted nanocomplex (scL);
机译:激活P53家族成员TAP63:一种靶向P53改变肿瘤的新型治疗策略
机译:通过操纵其家族成员p63和p73对p53改变的肿瘤进行新型治疗
机译:分子神经肿瘤学和针对脑肿瘤的靶向治疗策略的发展。第4部分:p53信号传导途径。
机译:P53肿瘤抑制剂损失损失低阈值的稳定性:P53四聚化结构域突变体的定量分析
机译:全基因组,高通量筛选确定核受体亚家族2的成员是肿瘤抑制p53的激活剂。
机译:激活p53家族成员TAp63:针对p53改变的肿瘤的新型治疗策略
机译:Hipk2 - 待肿瘤抑制激活的治疗靶标:P53激活和HIF-1α抑制中的作用