Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells

Kittai Adam; Best Scott R.; Rowland Taylor; Bruss Nur; Okada Craig; Danilov Alexey V.

首页> 外文期刊>Blood: The Journal of the American Society of Hematology >Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells

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Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells

机译：Pevonedistat，NEDD8活化酶（NAE）的小分子抑制剂，诱导细胞周期放松管治疗，临床灾难和T细胞淋巴瘤细胞凋亡

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来源
《Blood: The Journal of the American Society of Hematology》 |2018年第novaelatreatmentappr期|共2页
作者
Kittai Adam; Best Scott R.; Rowland Taylor; Bruss Nur; Okada Craig; Danilov Alexey V.;
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作者单位

Oregon Hlth &

Sci Univ Knight Canc Inst Portland OR 97201 USA;

Oregon Hlth &

Sci Univ Portland OR 97201 USA;

Oregon Hlth &

Sci Univ Portland OR 97201 USA;

Oregon Hlth &

Sci Univ Portland OR 97201 USA;

Oregon Hlth &

Sci Univ Portland OR 97201 USA;

Oregon Hlth &

Sci Univ Portland OR 97201 USA;

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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
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1. Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells [J] . Kittai Adam, Best Scott R., Rowland Taylor, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：Pevonedistat，NEDD8活化酶（NAE）的小分子抑制剂，诱导细胞周期放松管治疗，临床灾难和T细胞淋巴瘤细胞凋亡
2. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells [J] . Wang Yanchun, Luo Zhongguang, Pan Yongfu, Cancer biology & therapy . 2015,第3期

机译：用NEDD8激活酶抑制剂MLN4924靶向蛋白质凝结作用诱导人淋巴瘤细胞凋亡或衰老
3. DCZ3301, a novel aryl-guanidino inhibitor, Induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma [J] . Wenqin Xiao, Xiucai Lan, Zhijian Xu, 生物化学与生物物理学报：英文版 . 2018,第007期

机译：DCZ3301是一种新型的芳基胍基抑制剂，可通过抑制T细胞白血病/淋巴瘤中的PI3K / AKT途径来诱导细胞凋亡和细胞周期停滞
4. Roles of protein kinase C in radiation-induced apoptosis signaling pathways in murine thymic lymphoma cells (3SBH5 cells) [C] . Tetsuo Nakajim, Osami Yukaw, Harumi Ohyam, International Symposium of Radiation and Homeostasis . 2002

机译：蛋白激酶C在鼠胸腺淋巴瘤细胞辐射诱导的凋亡信号通路中的作用（3SBH5细胞）
5. Inhibition of NFkappaB in cutaneous T-cell lymphoma HUT-78 cells by nuclear translocation of IkappaBalpha induced by proteasome inhibitors. [D] . Juvekar, Ashish. 2010

机译：蛋白酶体抑制剂诱导的IkappaBalpha核转位抑制皮肤T细胞淋巴瘤HUT-78细胞中的NFkappaB。
6. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells [O] . Yanchun Wang, Zhongguang Luo, Yongfu Pan, 2015

机译：用NEDD8激活酶抑制剂MLN4924靶向蛋白质融合作用诱导人淋巴瘤细胞凋亡或衰老
7. DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma [O] . Wenqin Xiao, Bo Li, Xi Sun, 2018

机译：DCZ3301，一种新型芳基 - 胍蛋白抑制剂，通过抑制T细胞白血病/淋巴瘤中的PI3K / AKT途径诱导细胞凋亡和细胞周期停滞

Pevonedistat, a Small Molecule Inhibitor of NEDD8-Activating Enzyme (NAE), Induces Cell Cycle Deregulation, Anaphase Catastrophe, and Apoptosis in T-Cell Lymphoma Cells

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