A Direct Oral Anticoagulant Edoxaban Enhanced Fibrinolysis Via Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor Activation and Enhancement of Plasmin Generation in Human Plasma

Morishima Yoshiyuki; Honda Yuko; Furugohri Taketoshi

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A Direct Oral Anticoagulant Edoxaban Enhanced Fibrinolysis Via Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor Activation and Enhancement of Plasmin Generation in Human Plasma

机译：直接口服抗凝血剂Edoxaban通过抑制凝血酶活性纤维蛋白溶解剂活化和增强人血浆中的纤溶酶产生的增强纤维蛋白酶

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来源
《Blood: The Journal of the American Society of Hematology》 |2018年第novaelatreatmentappr期|共2页
作者
Morishima Yoshiyuki; Honda Yuko; Furugohri Taketoshi;
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作者单位

Daiichi Sankyo Co Ltd Tokyo Japan;

Daiichi Sankyo Co Ltd Tokyo Japan;

Daiichi Sankyo Co Ltd Tokyo Japan;

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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
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入库时间 2022-08-20 16:01:33

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专利

1. A Direct Oral Anticoagulant Edoxaban Enhanced Fibrinolysis Via Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor Activation and Enhancement of Plasmin Generation in Human Plasma [J] . Morishima Yoshiyuki, Honda Yuko, Furugohri Taketoshi Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：直接口服抗凝血剂Edoxaban通过抑制凝血酶活性纤维蛋白溶解剂活化和增强人血浆中的纤溶酶产生的增强纤维蛋白酶
2. Combined effect of a direct oral anticoagulant edoxaban and an inhibitor of activated thrombin-activatable fibrinolysis inhibitor on clot lysis [J] . Morishima Yoshiyuki, Kamisato Chikako, Honda Yuko Journal of thrombosis and thrombolysis . 2020,第1期

机译：直流抗凝血剂Edoxaban的综合作用及活化凝血酶可活化纤维蛋白溶解剂对凝块裂解的抑制作用
3. Paradoxical enhancement of the intrinsic pathway-induced thrombin generation in human plasma by melagatran, a direct thrombin inhibitor, but not edoxaban, a direct factor Xa inhibitor, or heparin [J] . Furugohri Taketoshi, Morishima Yoshiyuki Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2015,第3期

机译：通过直接的凝血酶抑制剂美加仑对人血浆中内在途径诱导的凝血酶生成的矛盾增强
4. Polymeric Nanoparticles Having Surface Cationic Moieties Enhance Oral Absorptionof DX-9065, A Novel Anticoagulant [C] . S. Sakuma, Y. Fujii, T. Kanamaru, Annual meeting exposition of the Controlled Release Society . 2005

机译：具有表面阳离子部分的聚合物纳米颗粒增强了新型抗凝剂DX-9065的口服吸收
5. Modeling of fibrinolysis and thrombin-activatable fibrinolysis inhibitor. [D] . Butler, Michael Jeffery. 2002

机译：纤维蛋白溶解和凝血酶激活的纤维蛋白溶解抑制剂的建模。
6. Activated platelet-based inhibition of fibrinolysis via thrombin-activatable fibrinolysis inhibitor activation system [O] . Yuko Suzuki, Hideto Sano, Liina Mochizuki, 2020

机译：通过凝血酶激活纤维蛋白溶解抑制剂活化系统活化血小板基纤维蛋白溶解
7. Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity [O] . X. Zhou, S. D. Weeks, P. Ameloot, 2016

机译：阐明抑制凝血酶活性纤维蛋白溶解抑制剂活化和活化凝血酶活化纤维蛋白溶解抑制剂活性的分子机制
8. Enhancement of Tissue Plasminogen Activator-Induced Fibrinolysis by ActivatedProtein C in Endotoxin-Treated Rabbits [R] . Krishnamurti, C., Young, G. D., Barr, C. F., 1991

机译：内毒素处理兔活化蛋白C增强组织型纤溶酶原激活物诱导的纤维蛋白溶解

A Direct Oral Anticoagulant Edoxaban Enhanced Fibrinolysis Via Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor Activation and Enhancement of Plasmin Generation in Human Plasma

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