Assessment of airborne and dermal exposure to 2-ethoxyethyl acetate in an occupational environment.

摘要

BACKGROUND: Because of its chemical-physical properties, 2-ethoxyethyl acetate (EEAc) can penetrate through the skin. However, no actual occupational environmental studies or empirical dermal exposure measurements have been performed. METHODS: Twenty workers from a commercial label silk screening shop were recruited and they completed a questionnaire of demographic information. Environmental monitoring of EEAc exposure via respiratory and dermal routes was performed for five consecutive working days. RESULTS: Airborne EEAc concentration was over the permissible exposure limit of 5 ppm in 90% of the participants. The dermal EEAc concentration was highest on the palms. The EEAc concentration correlated with skin exposure level (P < 0.001). The dermal EEAc concentrations in individuals who did not wear gloves were higher than in those who wore gloves. CONCLUSIONS: EEAc on the skin is strongly associated with airborne EEAc. Wearing impermeable gloves during high-risk tasks (cleaning process) can reduce EEAc dermal exposure on the palms.