Improved therapeutic effectiveness by combining recombinant p14(ARF) with antisense complementary DNA of EGFR in laryngeal squamous cell carcinoma

Liu Feng; Du JinTao; Xian Junming; Liu Yafeng; Liu Shixi; Lin Yan

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Improved therapeutic effectiveness by combining recombinant p14(ARF) with antisense complementary DNA of EGFR in laryngeal squamous cell carcinoma

机译：通过重组p14（ARF）与EGFR反义互补DNA联合治疗喉鳞状细胞癌，提高治疗效果

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Purpose: The tumor suppressor p14ARF and proto-oncogene epidermal growth factor receptor (EGFR) play important roles in the development of laryngeal squamous cell carcinoma pcq. This study was aimed to determine whether combining recombinant p14(ARF) with antisense complementary DNA of EGFR could improve the therapeutic effectiveness in LSCC.

机译：目的：抑癌基因p14ARF和原癌基因表皮生长因子受体（EGFR）在喉鳞状细胞癌pcq的发展中起重要作用。这项研究旨在确定重组p14（ARF）与EGFR的反义互补DNA结合是否可以提高LSCC的治疗效果。

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《American journal of otolaryngology》 |2015年第6期|共9页
作者
Liu Feng; Du JinTao; Xian Junming; Liu Yafeng; Liu Shixi; Lin Yan;
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正文语种 eng
中图分类耳鼻咽喉科学;
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1. Improved therapeutic effectiveness by combining recombinant p14(ARF) with antisense complementary DNA of EGFR in laryngeal squamous cell carcinoma [J] . Liu Feng, Du JinTao, Xian Junming, American journal of otolaryngology . 2015,第6期

机译：通过重组p14（ARF）与EGFR反义互补DNA联合治疗喉鳞状细胞癌，提高治疗效果
2. Aberrant gene promoter methylation of E-cadherin, p16(INK4a), p14(ARF), and MGMT in Epstein-Barr virus-associated oral squamous cell carcinomas [J] . Burassakarn Ati, Pientong Chamsai, Sunthamala Nuchsupha, Medical oncology . 2017,第7期

机译：E-Cadherin，P16（Ink4a），p14（ARF）和MgMT在Epstein-Barr病毒相关口腔鳞状细胞癌中的异常基因启动子甲基化
3. Analysis of methylation patterns and expression profiles of p14 ~(ARF) gene in patients with oral squamous cell carcinoma [J] . Kordi-Tamandani D.M., Moazeni-Roodi A., Ladez M.A.R., The International journal of biological markers . 2010,第2期

机译：口腔鳞癌患者p14〜（ARF）基因甲基化模式及表达谱分析
4. A novel functionalized chitosan-based nanoconstruct for targeted subcutaneous delivery of protein therapeutics in squamous cell carcinoma [C] . Samson Adeyemi World biomaterials congress . 2016

机译：一种新型的功能化壳聚糖为基础的纳米构造的鳞状细胞癌的蛋白质治疗剂的皮下靶向输送。
5. The role of ligand-independent activation of EGFR in E-cadherin-mediated squamous cell carcinoma cell survival. [D] . Shen, Xiaodong. 2003

机译：EGFR配体非依赖性激活在E-钙黏着蛋白介导的鳞状细胞癌细胞存活中的作用。
6. Combined EGFR/ALK Expression Analysis in Laryngeal Squamous Cell Carcinoma [O] . ANASTASIA POLITI, EVANGELOS TSIAMBAS, NICHOLAS S. MASTRONIKOLIS, 2019

机译：EGFR / ALK联合表达在喉鳞状细胞癌中的作用
7. Loss of p21 disrupts p14 ARF-induced G1 cell cycle arrest but augments p14 ARF-induced apoptosis in human carcinoma cells [O] . Hemmati, Philipp G., Normand, Guillaume, Verdoodt, Berlinda, 2005

机译：p21的缺失破坏了p14 ARF诱导的G1细胞周期阻滞，但增强了p14 ARF诱导的人癌细胞凋亡

Improved therapeutic effectiveness by combining recombinant p14(ARF) with antisense complementary DNA of EGFR in laryngeal squamous cell carcinoma

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