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Interventional diabetology: The evolution of diabetes care in the XXI century

机译:介入糖尿病学:二十一世纪糖尿病护理的演变

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It has been observed that bariatric surgery, in addition to its profound weight-reduction effects, leads to a durable resolution of type 2 diabetes. This supports the possibility that a cure for this disease may be obtainable, both by surgery as well as with drugs or devices that mimics the effects of surgery'. Elucidating the mechanisms underlying the beneficial effects of gastrointestinal surgery may also facilitate understanding of the elusive etiology of this condition. Current evidence supports a role for surgical interventions in the treatment algorithm of obese patients with type 2 diabetes, while a number of device-based gastrointestinal interventions are now being investigated as novel and less invasive alternatives. Interventional diabetology could be defined by the use and study of traditional surgical options and novel, gastrointestinal device- based interventions for diabetes. In this manuscript, we discuss how the introduction of interventional diabetology may shape the way we approach diabetes in the 21st century.
机译:据观察,减肥手术除具有深远的减肥效果外,还可以持久地治愈2型糖尿病。这支持了通过外科手术以及模仿外科手术效果的药物或器械均可治愈该疾病的可能性。阐明胃肠道手术有益作用的潜在机制也可能有助于了解这种情况的难以捉摸的病因。当前的证据支持外科手术干预在肥胖2型糖尿病患者的治疗算法中的作用,而许多基于设备的胃肠道干预目前正在作为新的且侵入性较小的替代方法进行研究。可以通过使用和研究传统的外科手术方法以及基于糖尿病的新型胃肠设备进行干预来定义介入性糖尿病。在本手稿中,我们讨论了介入性糖尿病学的引入如何影响我们在21世纪应对糖尿病的方式。

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