Analyzing the Amperometric Response of a Glucose Oxidase Sensor Applying Mathematical Models

摘要

Background: The biosensors are analytical devices combining a bioreceptor and a physicochemical transducer to translate the signal resulting from the interaction of the analyte with the biological element into an electrical reading. The technological attractiveness of the biosensors resides in their high sensitivity, continuous measuring capabilities, low cost, and precision. An important and promising area of biosensors application is the associated with blood glucose levels monitoring in diabetic patients. However, accuracy and stability issues are still under development, impeding the more widespread offering of glucose biosensors in the market. Thus, this work aims to contribute to the biosensors technology by analyzing the amperometric response to glucose of a typical glucose oxidase-based sensor of second generation, applying mathematical models.