CD10，CD99の免疫組織学的検討を行ったatypical fibroxanthomaの1例

摘要

The patient was a 56-year-old man who had a 1cm nodule on his left cheek. The tumor was simply excised at the former hospital, but two months after that excision, recurrence resulted. Then, in our hospital, this lesion was removed on the surface of the muscle with surgical margin of about lcm and trilobed flap was used for wound closure. The pathological diagnosis was recurrent atypical fibroxanthoma. After the operation, we examined immunoreactivity to CD10 and CD99 for a specimen of the simple excision. For 10 months after our surgery, there was no recurrence or metastasis.Atypical fibroxanthoma occurs mostly on the head and neck of elderly people. It is characterized as following a benign clinical course despite its histological appearance.Histological differential diagnoses for atypical fibroxanthoma include malignant fibrous histiocytoma, squamous cell carcinoma, and malignant melanoma. Recently, immu no hi sto chemical markers CD10 and CD99 are thought to be useful in diagnosis.