Effect of oatmeal supplementation on the serum cholesterol levels in adults with boundary and mild hypercholesterolemia.

摘要

74 Japanese men and 19 women were randomly assigned to groups treated with either a placebo or oatmeal. The oatmeal group was given porridge containing 60 g of oatmeal (21 g of beta -glucan), and the placebo group was given porridge containing white rice and cellulose for 12 weeks each. The serum biochemical indices of each subject were measured at the start, after 4, 8 and 12 weeks of treatment, and 4 weeks after the end of the study. The daily intake of nutrients was monitored by a 3-day food record made at the start, after 4, 8 and 12 weeks of treatment, and 4 weeks after the end of the study. The decrease in the serum total cholesterol level was significantly different between the placebo and oatmeal groups throughout the supplementation period (P<0.05), with a similar difference in the non-high density lipoprotein cholesterol levels. There was no haematological, physical, or clinical difference indicative of any adverse reaction between the groups given the test porridge. The results indicate that supplementation with oatmeal at 60 g/day (2.1 g of beta -glucan/day) decreased the serum total cholesterol levels in Japanese adults with boundary and mild hypercholesterolaemia..