Efficacy and safety of dapagliflozin or dapagliflozin plus saxagliptin versus glimepiride as add-on to metformin in patients with type 2 diabetes

Mueller-Wieland Dirk; Kellerer Monika; Cypryk Katarzyna; Skripova Dasa; Rohwedder Katja; Johnsson Eva; Garcia-Sanchez Ricardo; Kurlyandskaya Raisa; Sjostrom C. David; Jacob Stephan; Seufert Jochen; Dronamraju Nalina; Csomos Katalin

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Efficacy and safety of dapagliflozin or dapagliflozin plus saxagliptin versus glimepiride as add-on to metformin in patients with type 2 diabetes

机译：Dapagliflozin或Dapagliflozin Plus Saxagliptin对2型糖尿病患者的加载作用的含量为甲状腺素的疗效和安全性

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Objective: To compare the efficacy and safety of dapagliflozin and dapagliflozin plus saxagliptin vs glimepiride as add-on to metformin in patients with type 2 diabetes.

机译：目的：比较Dapagliflozin和Dapagliflozin Plus Saxagliptin Vs Glimepiride作为2型糖尿病患者加载作用的疗效和安全性。

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来源
《Diabetes, obesity & metabolism》 |2018年第11期|共10页
作者
Mueller-Wieland Dirk; Kellerer Monika; Cypryk Katarzyna; Skripova Dasa; Rohwedder Katja; Johnsson Eva; Garcia-Sanchez Ricardo; Kurlyandskaya Raisa; Sjostrom C. David; Jacob Stephan; Seufert Jochen; Dronamraju Nalina; Csomos Katalin;
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作者单位

Rhein Westfal TH Aachen Univ Hosp Dept Med 1 Pauwelsstr 30 D-52074 Aachen Germany;

Marienhospital Zentrum Innere Med 1 Stuttgart Germany;

Med Univ Lodz Dept Internal Med &

Diabetol Lodz Poland;

DIAMEL Outpatient Clin Diabet &

Metab Trencin Slovakia;

AstraZeneca Wedel Germany;

AstraZeneca Gothenburg Molndal Sweden;

AstraZeneca Gaithersburg MD USA;

AstraZeneca Gothenburg Molndal Sweden;

AstraZeneca Gothenburg Molndal Sweden;

Cardiometab Inst Villingen Schwenningen Germany;

Univ Freiburg Fac Med Dept Med 2 Div Endocrinol &

Diabetol Med Ctr Freiburg Germany;

AstraZeneca Gaithersburg MD USA;

CRU Hungary Kft Miskolc Hungary;

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原文格式 PDF
正文语种 eng
中图分类内分泌腺疾病及代谢病;
关键词
dapagliflozin; DPP-IV inhibitor; phase III study; SGLT2 inhibitor; sulphonylureas; type 2 diabetes;

机译：Dapagliflozin;DPP-IV抑制剂;III期研究;SGLT2抑制剂;磺酰脲类;2型糖尿病;

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专利

1. Efficacy and safety of dapagliflozin or dapagliflozin plus saxagliptin versus glimepiride as add-on to metformin in patients with type 2 diabetes [J] . Mueller-Wieland Dirk, Kellerer Monika, Cypryk Katarzyna, Diabetes, obesity & metabolism . 2018,第11期

机译：Dapagliflozin或Dapagliflozin Plus Saxagliptin对2型糖尿病患者的加载作用的含量为甲状腺素的疗效和安全性
2. Sustained 52‐week efficacy and safety of triple therapy with dapagliflozin plus saxagliptin versus dual therapy with sitagliptin added to metformin in patients with uncontrolled type 2 diabetes [J] . Handelsman Yehuda, Mathieu Chantal, Del Prato Stefano, Diabetes, obesity & metabolism . 2019,第4期

机译：用Dapagliflozin加saxagliptin与Saxagliptin与SitaGliptin的双重治疗持续52周的疗效和安全性，在不受控制的2型糖尿病患者中添加到二甲双胍中
3. Dapagliflozin versus saxagliptin as add-on therapy in patients with type 2 diabetes inadequately controlled with metformin [J] . Julio?Rosenstock, Chantal?Mathieu, Hungta?Chen, Archives of Endocrinology and Metabolism . 2018,第4期

机译：Dapagliflozin与saxagliptin作为二甲双胍控制不足的2型糖尿病患者的附加治疗
4. The Comparative Effect of Pomegranate Peel Extract and Dapagliflozin on Body Weight of Male Albino Wistar Rats with Type 2 Diabetes Mellitus [C] . Devi Trisna Ramadhani, Rafi Amanda Rezkia Amradani, Mila Ulfia Annual Basic Science International Conference . 2019

机译：石榴果皮提取物和Dapagliflozin对2型糖尿病雄性白化Wistar大鼠体重的对比作用
5. Development and Validation of a New Combination: Dapagliflozin, Pioglitazone and Metformin Simultaneously in Tablets Dosage Form by HPLC [D] . Al-Arjani, Ramzi Amirah. 2021

机译：新组合的开发和验证：Dapagliflozin，Pioglitazone和二甲双胍在单片药物用HPLC中的剂量形式
6. Efficacy and safety of dapagliflozin or dapagliflozin plus saxagliptin versus glimepiride as add‐on to metformin in patients with type 2 diabetes [O] . Dirk Müller‐Wieland, Monika Kellerer, Katarzyna Cypryk, -1

机译：达格列净或达格列净加沙格列汀与格列美脲联合二甲双胍治疗2型糖尿病的疗效和安全性
7. Efficacy and safety of dual add‐on therapy with dapagliflozin plus saxagliptin versus glimepiride in patients with poorly controlled type 2 diabetes on a stable dose of metformin: Results from a 52‐week, randomized, active‐controlled trial [O] . Juan P. Frias, Guillermo Gonzalez‐Galvez, Eva Johnsson, 2020

机译：双加入治疗与Dapagliflozin Plus Saxagliptin对稳定剂量的二甲双胍的患者患者的疗效和安全性与肺炎素蛋白在稳定剂量的二甲双胍上的患者中：结果由52周，随机的，主动控制的试验

Efficacy and safety of dapagliflozin or dapagliflozin plus saxagliptin versus glimepiride as add-on to metformin in patients with type 2 diabetes

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