The effect of adipose-derived stem cells on enthesis healing after repair of acute and chronic massive rotator cuff tears in rats

Rothrauff Benjamin B.; Smith Catherine A.; Ferrer Gerald A.; Novaretti Joao V; Pauyo Thierry; Chao Tom; Hirsch David; Beaudry Mason F.; Herbst Etmar; Tuan Rocky S.; Debski Richard E.; Musahl Volker

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The effect of adipose-derived stem cells on enthesis healing after repair of acute and chronic massive rotator cuff tears in rats

机译：脂肪衍生的干细胞对大鼠急性和慢性大规模旋转箍撕裂后肠杆菌愈合的影响

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Background: Chronic massive rotator cuff tears heal poorly and often retear. This study investigated the effect of adipose-derived stem cells (ADSCs) and transforming growth factor-beta 3 (TGF-beta 3) delivered in 1 of 2 hydrogels (fibrin or gelatin methacrylate [GelMA]) on enthesis healing after repair of acute or chronic massive rotator cuff tears in rats.

机译：背景：慢性大规模转子袖口撕裂愈合不善，经常固定。本研究研究了脂肪衍生的干细胞（ADSCs）和转化在急性或修复后在2个水凝胶（纤维蛋白或明胶甲酸甲酯[GELMA]）中的生长因子-β3（TGF-BETA 3）的生长因子-β3（TGF-β3）的影响。慢性大规模转子袖口撕裂大鼠。

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来源
《Journal of shoulder and elbow surgery》 |2019年第4期|共11页
作者
Rothrauff Benjamin B.; Smith Catherine A.; Ferrer Gerald A.; Novaretti Joao V; Pauyo Thierry; Chao Tom; Hirsch David; Beaudry Mason F.; Herbst Etmar; Tuan Rocky S.; Debski Richard E.; Musahl Volker;
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作者单位

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Bioengn Pittsburgh PA USA;

Univ Pittsburgh Dept Bioengn Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

Univ Pittsburgh Dept Orthopaed Surg Pittsburgh PA USA;

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原文格式 PDF
正文语种 eng
中图分类四肢外科学;
关键词
Shoulder; rotator cuff; mesenchymal stem cell; enthesis; chronicity; augmented repair; rat;

机译：肩部;旋转器袖带;间充质干细胞;禁止;慢性;增强修复;老鼠;

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专利

1. The effect of adipose-derived stem cells on enthesis healing after repair of acute and chronic massive rotator cuff tears in rats [J] . Rothrauff Benjamin B., Smith Catherine A., Ferrer Gerald A., Journal of shoulder and elbow surgery . 2019,第4期

机译：脂肪衍生的干细胞对大鼠急性和慢性大规模旋转箍撕裂后肠杆菌愈合的影响
2. Mesenchymal Stem Cell Secretome Improves Tendon Cell Viability In Vitro and Tendon-Bone Healing In Vivo When a Tissue Engineering Strategy Is Used in a Rat Model of Chronic Massive Rotator Cuff Tear [J] . Nuno Sevivas, Fábio Gabriel Teixeira, Raquel Portugal, American Journal of Sports Medicine . 2018,第2期

机译：间充质干细胞沉淀在组织工程策略用于慢性大规模旋转箍撕裂的大鼠模型时，在体外和肌腱 - 骨愈合的体外和肌腱骨愈合
3. Chronic Degeneration Leads to Poor Healing of Repaired Massive Rotator Cuff Tears in Rats [J] . Killian Megan L., Cavinatto Leonardo M., Ward Samuel R., American Journal of Sports Medicine . 2015,第10期

机译：慢性变性导致大鼠修复的大型肩袖撕裂的愈合不良
4. RESTORATION OF SHOULDER BIOMECHANICS IN THE MASSIVE ROTATOR CUFF TEAR ACCORDING TO DEGREE OF REPAIR COMPLETION [C] . Bong Jae Jun, Joo Han Oh, Michelle H. McGarry, 5th frontiers in biomedical devices conference and exposition 2010 . 2010

机译：根据修复的完成程度，修复大转子胎撕裂中的肩部生物力学
5. The role of tension on supraspinatus tendon to bone healing in a newly developed animal model of chronic rotator cuff tears. [D] . Gimbel, Jonathan A. 2005

机译：在新开发的慢性肩袖撕裂动物模型中，张力对棘上肌腱对骨愈合的作用。
6. The Effect of Adipose-derived Mesenchymal Stem Cells on Healing of Massive Chronic Rotator Cuff Tear in Rodent Model [O] . Thierry Pauyo, Benjamin B. Rothrauff, Tom Chao, -1

机译：啮齿动物模型中脂肪来源的间充质干细胞对大面积慢性转子袖撕裂愈合的影响
7. The Effect of Adipose-derived Mesenchymal Stem Cells on Healing of Massive Chronic Rotator Cuff Tear in Rodent Model [O] . Thierry Pauyo, Benjamin B. Rothrauff, Tom Chao, 2017

机译：脂肪衍生间充质干细胞对啮齿动物模型大规模慢性旋转箍腹部愈合的影响

The effect of adipose-derived stem cells on enthesis healing after repair of acute and chronic massive rotator cuff tears in rats

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