Liquid chromatographic resolution of proline and pipecolic acid derivatives on chiral stationary phases based on (+)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid

Cho Eun Sol; Sung Ji Yeong; Jin Jong Sung; Hyun Myung Ho

摘要

Abstract > Two liquid chromatographic chiral stationary phases based on (+)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid were applied to the resolution of the amide derivatives of cyclic α‐amino acids including proline and pipecolic acid. Among the five amide derivatives of proline, aniline amide was resolved best on the first chiral stationary phase, which contains two N–H tethering amide groups, with the separation factor of 1.31 and the resolution of 2.60, and on the second chiral stationary phase, which contains two N–CH <sub>3</sub> tethering amide groups, with the separation factor of 1.57 and the resolution of 5.50. Among the five amide derivatives of pipecolic acid, 2‐naphthyl amide was resolved best on the first chiral stationary phase with the separation factor of 1.30 and the resolution of 1.75, but 1‐naphthylmethyl amide was resolved best on the second chiral stationary phase with the separation factor of 1.30 and the resolution of 2.26. In general, the second chiral stationary phase was found to be better than the first chiral stationary phase in the resolution of the amide derivatives of cyclic α‐amino acids. In this study, the second chiral stationary phase was first demonstrated to be useful for the resolution of secondary amino compounds. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>抽象</ title> >两个基于（+） - （18-Crown-6）的液体色谱手性固定阶段将-2,3,11,12-四羧酸施加到包括脯氨酸和哌啶醇的环状α-氨基酸的酰胺衍生物的分辨率。在脯氨酸的五个酰胺衍生物中，苯胺酰胺在第一种手性固定阶段中最佳地分解，其含有两个N-H束缚酰胺基团，分离因子为1.31，分辨率为2.60，以及第二个手续的固定阶段，其中包含两个N-CH <亚> 3 </ sub>酰胺基团，分离因子为1.57，分辨率为5.50。在哌啶醇的五个酰胺衍生物中，最佳的第一个手性固定相位溶解2-萘基酰胺，分离因子为1.30，分辨率为1.75，但在第二个手性固定阶段最佳地解决了1-萘基甲基酰甲基酰甲基酰甲基甲基甲基酰氨基分离因子为1.30，分辨率为2.26。通常，发现第二型手性固定相比循环α-氨基酸的酰胺衍生物的分辨率更好地优于第一个手性固定相。在该研究中，首先证明第二人手性固定相对于仲氨基化合物的分辨率有用。 </ p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" > 著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-35800/'>《Journal of separation science. 》</a> <b style="margin: 0 2px;">|</b><span>2018年第6期</span><b style="margin: 0 2px;">|</b> <span>共7页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Cho Eun Sol&option=202" target="_blank" rel="nofollow">Cho Eun Sol;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sung Ji Yeong&option=202" target="_blank" rel="nofollow">Sung Ji Yeong;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jin Jong Sung&option=202" target="_blank" rel="nofollow">Jin Jong Sung;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Hyun Myung Ho&option=202" target="_blank" rel="nofollow">Hyun Myung Ho;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of ChemistryPusan National UniversityBusan Republic of Korea;</p> <p>Busan CenterKorea Basic Science InstituteBusan Republic of Korea;</p> <p>Busan CenterKorea Basic Science InstituteBusan Republic of Korea;</p> <p>Department of ChemistryPusan National UniversityBusan Republic of Korea;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li> <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span> <a href="https://www.zhangqiaokeyan.com/clc/159.html" title="化学">化学 ;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=chiral stationary phases&option=203" rel="nofollow">chiral stationary phases;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=enantiomer separation&option=203" rel="nofollow">enantiomer separation;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=liquid chromatography&option=203" rel="nofollow">liquid chromatography;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=pipecolic acid&option=203" rel="nofollow">pipecolic acid;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=proline&option=203" rel="nofollow">proline;</a> </p> <div class="translation"> 机译：手性固定阶段;对映体分离;液相色谱;吡啶酸;脯氨酸; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025846553.html">Liquid chromatographic resolution of proline and pipecolic acid derivatives on chiral stationary phases based on (+)‐(18‐crown‐6)‐2,3,11,12‐tetracarboxylic acid</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Cho Eun Sol&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Cho Eun Sol,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sung Ji Yeong&option=202" target="_blank" rel="nofollow" class="tuijian_auth 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style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：基于（+） - （18-冠-6）-2,3,11,12-四羧酸的手性固定相上的Fendiline及其类似物的液相色谱分离</span> </p> </li> <li> <div> <b>8. </b><a class="enjiyixqcontent" href="/ntis-science-report_de_thesis/02071860810.html">Using 15-crown-5, 18-crown-6 and dicyclohexano-18-crown-6 for Am, Ce, Eu and Cm extraction from acid solutions</a> <b>[R] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Romanovski, V. V. &option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Romanovski, V. V. ,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Proyaev, V. V. &option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Proyaev, V. V. ,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wester, D. W.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Wester, D. W. </a> <span>1994</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：使用15-冠-5,18-冠-6和二环己烷-18-冠-6从酸溶液中提取am，Ce，Eu和Cm</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chemical-journal-chinese-universities_thesis/0201231643889.html">高效液相色谱手性固定相对氨基酸衍生物对映体分离研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=沈含熙&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 沈含熙</a> <span> <a href="/journal-cn-10958/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 高等学校化学学报 </a> </span> <span> . 1995</span><span> ,第007期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-chromatography_thesis/0201246793587.html">L-脯氨酸衍生物为手性侧链的新型C2对称型手性固定相</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陈龙&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 陈龙</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=程玲平&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,程玲平</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=何珊珊&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,何珊珊</a> <span> <a href="/journal-cn-14390/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 色谱 </a> </span> <span> . 2017</span><span> ,第007期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-chromatography_thesis/0201247239545.html">高效液相色谱手性固定相的研究Ⅴ——二肽叔丁酰胺型手性固定相拆分α-氨基酸、二茂铁基氨基酸及二肽衍生物对映异构体</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘晋钫&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 刘晋钫</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=徐修容&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,徐修容</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=黄嘉鑫&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,黄嘉鑫</a> <span> <a href="/journal-cn-14390/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 色谱 </a> </span> <span> . 1990</span><span> ,第004期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_acta-chimica-sinica_thesis/0201294218913.html">高效液相色谱手性固定相的研究 Ⅳ.(L,L)-二肽叔丁酰胺型手性固定相拆分α-氨基烃基膦酸衍生物对映异构体</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘晋钫&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 刘晋钫</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=徐修容&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,徐修容</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=黄嘉鑫&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,黄嘉鑫</a> <span> <a href="/journal-cn-53859/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 化学学报 </a> </span> <span> . 1990</span><span> ,第10期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-analytical-chemistry_thesis/0201230620903.html">手性胺酰胺型液相色谱手性固定相的制备及几种氨基酸衍生物的拆分</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=谭徐林&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 谭徐林</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=侯士聪&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,侯士聪</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王敏&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,王敏</a> <span> <a href="/journal-cn-10804/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 分析化学 </a> </span> <span> . 2007</span><span> ,第006期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-12010_thesis/02022526212.html">含a-氨基膦酸酯的哒嗪酮类衍生物对映体在多糖类手性固定相上的高效液相色谱分离</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张晓燕&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 张晓燕</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张钰萍&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张钰萍</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=宋宝安&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,宋宝安</a> <span> <a href="/conference-cn-12010/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国化学会第三届全国分子手性学术研讨会 </a> <span> <span> . 2010</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020312086311.html">螺旋聚苯乙炔负载脯氨酸衍生物手性催化剂的合成与性能研究</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=薄思圆&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 薄思圆</a> <span> . 2018</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/061203831731.html">用于手性羧酸对映体识别和纯度分析的手性四苯乙烯四胺</a> <b>[P]</b> . <span> 中国专利： CN110407708B </span> <span> . 2020.07.10</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120101261074.html">用于手性羧酸对映体识别和纯度分析的手性四苯乙烯四胺</a> <b>[P]</b> . <span> 中国专利： CN110407708A </span> <span> . 2019-11-05</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130442607555.html">Process for preparing (-)-(18-crown-6)-2,3,11,12-tetracarboxylic acid, and (-)-chiral stationary phases for resolution of racemic compounds using the same</a> <b>[P]</b> . <span> 外国专利：  US2004044231A1 </span> <span> . 2004-03-04</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：制备（-）-（18-冠-6）-2,3,11,12-四羧酸和（-）-手性固定相以拆分外消旋化合物的方法 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130440289490.html">Process for preparing (-)-(18-crown-6)-2,3,11,12-tetracarboxylic acid, and (-)-chiral stationary phases for resolution of racemic compounds using the same</a> <b>[P]</b> . <span> 外国专利：  US6818778B2 </span> <span> . 2004-11-16</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：制备（-）-（18-冠-6）-2,3,11,12-四羧酸和（-）-手性固定相以拆分外消旋化合物的方法 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130443812254.html">Process for preparing (-)-(18-Crown-6)-2,3,11,12-tetracarboxylic acid, and (-)-chiral stationary phases for resolution of racemic compounds using the same</a> <b>[P]</b> . <span> 外国专利：  KR100390765B1 </span> <span> . 2003-07-10</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：制备（-）-（18-Crown-6）-2,3,11,12-四羧酸和（-）-手性固定相以拆分外消旋化合物的方法 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div 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