Malignant Peripheral Nerve Sheath Tumors of the Pericardium in a Patient with Neuroflbromatosis Type 1: The Diagnostic ^z>Value of ~(18)F-FDG PET/CT and ~(123)I-MIBG SPECT/CTMathieu Charest, Josephine Pressacco, and Jaramie Thomas-Gittens

摘要

A 25-y-old woman with known neurofibromatosis type 1 and a large anterior mediastinal mass was investigated. ~(18)F-FDG PET/CT revealed a radiotracer-avid anterior mediastinal mass having an SUV_(max) of 4.3 and demonstrating a hypoactive center. The ~(123)l-metaiodobenzylguanidine SPECT/CT study performed subsequently did not demonstrate any uptake, thereby excluding, for the most part, the diagnosis of paraganglioma or neuroblastoma. At final pathology, a malignant peripheral nerve sheath tumor of the pericardium with areas of chondro-sarcomatous and angiosarcomatous differentiation was diagnosed.