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首页> 外文期刊>Journal of pharmaceutical health services research: >Medicines dispensers' knowledge on the implementation of an artemisinin‐based combination therapy policy for the treatment of uncomplicated malaria in Tanzania
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Medicines dispensers' knowledge on the implementation of an artemisinin‐based combination therapy policy for the treatment of uncomplicated malaria in Tanzania

机译:药物分配对坦桑尼亚未复杂疟疾治疗的基于青蒿素的组合治疗政策的实施

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Abstract Objectives In 2005, Tanzania changed its policy for uncomplicated malaria treatment from sulphadoxine–pyrimethamine ( SP ) to artemisinin‐based combination therapy ( ACT ), specifically artemether–lumefantrine ( ALU ). SP remains the medicine of choice for intermittent preventive treatment in pregnancy ( IPT p). There is a need to assess dispensers' knowledge regarding the treatment of uncomplicated malaria and IPT p in Tanzania given appreciable self‐purchasing to improve future care. Methods Descriptive cross‐sectional design with structured questionnaires to capture quantitative data, with qualitative data captured using focus groups. The study was performed at 32 private pharmacies and 33 Accredited Drug Dispensing Outlets in the Nyamagana and Sengerema Districts in Tanzania, with 20 dispensers included in the qualitative discussions. Key findings The knowledge level of dispensers in the private medicine outlets was variable. Most dispensers knew ALU was first‐line treatment in uncomplicated malaria, however variable knowledge about taking ALU with fatty meals. Generally, dispensers had poor knowledge about dosing intervals for SP in IPT p and variable knowledge regarding treatments in the first trimester. Overall, 49% had good knowledge and 48% had moderate knowledge of ACT in uncomplicated malaria. There was a significant relationship between dispenser type and knowledge of ACT but no statistical relationship between the level of knowledge on IPT p and the dispenser. Conclusions The majority of dispensers in private medicines outlets have good knowledge on ACT policy in the treatment of uncomplicated malaria; however, few dispensers had good knowledge on IPT p, which may contribute to irrational dispensing of SP . This needs addressing given the extent of self‐purchasing in Tanzania.
机译:摘要目标2005年,坦桑尼亚改变了硫烷酮 - 吡米甲胺(SP)对氨基锡的联合治疗(ACT),特别是Artemether-Lumefantrine(ALU)的简单疟疾治疗政策。 SP仍然是怀孕中间歇性预防治疗的首选药物(IPT P)。有必要评估坦桑尼亚在坦桑尼亚的不复杂疟疾和IPT P的治疗的分配器知识,以便提高未来的护理。方法采用结构化问卷的描述性横截面设计捕获定量数据,使用焦点组捕获定性数据。该研究在32名私人药房和33个坦桑尼亚的尼马哈尼亚和斯万格马地区进行了33个认可的药物分配网点,其中包括20个分配器,包括在定性讨论中。主要发现私人药店中的分配器的知识水平是可变的。大多数分配器知道Alu在简单的疟疾中是一线治疗,无论有关于服用脂肪粉的可变知识。通常,分配器对IPT P中SP的给药间隔的知识差,以及关于孕中期治疗的可变知识。总体而言,49%有良好的知识,48%的人在简单的疟疾中的行为中等了解。分配器类型与行为知识之间存在重大关系,但在IPT P和分配器上的知识水平之间没有统计关系。结论私人药品网点中的大多数分配器对治疗简单疟疾治疗的良好知识;然而,很少有分配器对IPT P具有良好的知识,这可能有助于SP的非理性分配。鉴于坦桑尼亚的自购买程度,这需要解决。

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