Tolerability of Topical Tocilizumab Eyedrops in Dogs: A Pilot Study

Bunya Vatinee Y.; Iwabe Simone; Macchi Ilaria; Massaro-Giordano Mina; Pistilli Maxwell; Aguirre Gustavo D.

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Tolerability of Topical Tocilizumab Eyedrops in Dogs: A Pilot Study

机译：宠物中局部托管耳蜗的可耐受性：试点研究

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摘要

Purpose: The aim of this study was to examine the tolerability of topical tocilizumab eyedrops in normal dogs and to assess whether this preparation alters tear film cytokine levels or conjunctival cytokine mRNA expression.

机译：目的：本研究的目的是研究局部狗常规狗的潜意毒素眼镜的可耐受性，并评估该制剂是否改变泪膜细胞因子水平或结膜细胞因子mRNA表达。

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来源
《Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics》 |2017年第7期|共6页
作者
Bunya Vatinee Y.; Iwabe Simone; Macchi Ilaria; Massaro-Giordano Mina; Pistilli Maxwell; Aguirre Gustavo D.;
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作者单位

Univ Penn Scheie Eye Inst Perelman Sch Med Dept Ophthalmol 51N 39th St Philadelphia PA 19104;

Univ Penn Sch Vet Med Sect Ophthalmol Dept Clin Studies Philadelphia PA 19104 USA;

Univ Campus Biomed Rome Rome Italy;

Univ Penn Scheie Eye Inst Perelman Sch Med Dept Ophthalmol 51N 39th St Philadelphia PA 19104;

Univ Penn Scheie Eye Inst Perelman Sch Med Dept Ophthalmol 51N 39th St Philadelphia PA 19104;

Univ Penn Sch Vet Med Sect Ophthalmol Dept Clin Studies Philadelphia PA 19104 USA;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
dry eye; tocilizumab; topical; eyedrops; canine; dog; interleukin-6;

机译：干眼;拍照;局部;眼镜;犬;狗;白细胞介素-6;

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1. Tolerability of Topical Tocilizumab Eyedrops in Dogs: A Pilot Study [J] . Bunya Vatinee Y., Iwabe Simone, Macchi Ilaria, Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics . 2017,第7期

机译：宠物中局部托管耳蜗的可耐受性：试点研究
2. A Pilot Study to Assess Tolerability of Early Enteral Nutrition via Esophagostomy Tube Feeding in Dogs with Severe Acute Pancreatitis [J] . C.S. Mansfield, F.E. James, I.D. Robertson, Journal of Veterinary Internal Medicine . 2011,第3期

机译：通过食管造口管喂养评估重症急性胰腺炎犬早期肠内营养耐受性的初步研究
3. Clinical evidence on the efficacy and tolerability of a topical medical device containing benzoylperoxide 4%, retinol 0.5%, mandelic acid 1% and lactobionic acid 1% in the treatment of mild facial acne: an open label pilot study [J] . Virginia Garofalo, Maria Vittoria Cannizzaro, Sara Mazzilli, Clinical, Cosmetic and Investigational Dermatology . 2019,第10期

机译：含有4％苯甲酰过氧化物，0.5％视黄醇，1％扁桃酸和1％乳糖酸的局部医疗器械在治疗轻度面部痤疮中的功效和耐受性的临床证据：一项开放性试验研究
4. Delaying When all Dogs to go to Heaven: Virtual Reality Canine Anatomy Education Pilot Study [C] . Xuanhui Xu, Eleni Mangina, David Kilroy, IEEE Games, Entertainment, Media Conference . 2018

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5. Accelerated Orthodontic Tooth Movement With Flapless Corticotomy: A Pilot Study in Beagle Dogs. [D] . Hao, Jianjun. 2011

机译：无瓣皮瓣切开术加速牙齿正畸运动：比格犬的一项初步研究。
6. Tolerability of Topical Tocilizumab Eyedrops in Dogs: A Pilot Study [O] . Vatinee Y. Bunya, Simone Iwabe, Ilaria Macchi, -1

机译：狗局部外用托珠单抗滴眼液的耐受性：一项初步研究
7. Tolerability of Topical Tocilizumab Eyedrops in Dogs: A Pilot Study [O] . Vatinee Y. Bunya, Simone Iwabe, Ilaria Macchi, 2017

机译：宠物中的局部托运耳蜗的可容忍性：试点研究
8. Results of a Maximum Tolerated Dose Study in Dogs and a 14-day Oral Dose Tolerability Study in Rats. [R] . 2011

机译：狗的最大耐受剂量研究结果和大鼠14天口服剂量耐受性研究。

Tolerability of Topical Tocilizumab Eyedrops in Dogs: A Pilot Study

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