Off-target evaluation of LTR targeted anti-HIV CRISPR/Cas9 therapy

Link Robert; Nonnemacher Michael; Wigdahl Brian; Dampier Will

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Off-target evaluation of LTR targeted anti-HIV CRISPR/Cas9 therapy

机译：LTR靶向抗HIV CRISPR / CAS9治疗的偏离目标评估

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来源
《Journal of neurovirology 》 |2018年第1期| 共1页
作者
Link Robert; Nonnemacher Michael; Wigdahl Brian; Dampier Will;
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作者单位

Drexel Univ Sch Biomed Engn &

Hlth Syst Philadelphia PA 19104 USA;

Drexel Univ Coll Med Inst Mol Med &

Infect Dis Dept Microbiol &

Immunol Philadelphia PA 19104;

Drexel Univ Coll Med Inst Mol Med &

Infect Dis Dept Microbiol &

Immunol Philadelphia PA 19104;

Drexel Univ Coll Med Inst Mol Med &

Infect Dis Dept Microbiol &

Immunol Philadelphia PA 19104;

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原文格式 PDF
正文语种 eng
中图分类神经病学 ;
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专利

1. Off-target evaluation of LTR targeted anti-HIV CRISPR/Cas9 therapy [J] . Link Robert, Nonnemacher Michael, Wigdahl Brian, Journal of neurovirology . 2018 ,第Suppla1期

机译：LTR靶向抗HIV CRISPR / CAS9治疗的偏离目标评估
2. Cas9 Cuts and Consequences; Detecting, Predicting, and Mitigating CRISPR/Cas9 On- and Off-Target Damage Techniques for Detecting, Predicting, and Mitigating the On- and off-target Effects of Cas9 Editing [J] . Newman Anthony, Storrs Lora, Burgio Gaetan BioEssays : . 2020 ,第9期

机译：Cas9削减和后果; 检测，预测和减轻CRISPR / CAS9和偏离目标损坏技术，用于检测，预测和减轻CAS9编辑的开启和离心效果
3. CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences [J] . Lin Yanni, Cradick Thomas J., Brown Matthew T., Nucleic Acids Research . 2014 ,第11期

机译：CRISPR / CAS9系统在靶DNA与指导RNA序列之间的插入或缺失具有脱靶活动
4. Searching for Potential gRNA Off-Target Sites for CRISPR/Cas9 Using Automata Processing Across Different Platforms [C] . Chunkun Bo, Vinh Dang, Elaheh Sadredini, IEEE International Symposium on High Performance Computer Architecture . 2018

机译：使用跨不同平台的自动机处理搜索CRISPR / Cas9的潜在gRNA脱靶位点
5. Chromothripsis as an On-Target Consequence of CRISPR–Cas9 Genome Editing [D] . Leibowitz, Mitchell L. 2021

机译：Chromothripsis作为CRISPR-CAS9基因组编辑的目标后果
6. Evaluation of the CRISPR/Cas9 Genetic Constructs in Efficient Disruption of Porcine Genes for Xenotransplantation Purposes Along with an Assessment of the Off-Target Mutation Formation [O] . Natalia Ryczek, Magdalena Hryhorowicz, Daniel Lipiński, 2020

机译：CRISPR / Cas9基因构建体在异种移植目的猪基因有效破坏中的评估以及脱靶突变形成的评估
7. Detection of on-target and off-target mutations generated by CRISPR/Cas9 and other sequence-specific nucleases [O] . Zischewski, Julia, Fischer, Rainer, Bortesi, Luisa 2017

机译：检测CRISPR / Cas9和其他序列特异性核酸酶产生的靶上和靶外突变

Off-target evaluation of LTR targeted anti-HIV CRISPR/Cas9 therapy

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