Mycobacteria-specific cytokine responses as correlates of treatment response in active and latent tuberculosis

Clifford Vanessa; Tebruegge Marc; Zufferey Christel; Germano Susie; Forbes Ben; Cosentino Lucy; McBryde Emma; Eisen Damon; Robins-Browne Roy; Street Alan; Denholm Justin; Curtis Nigel

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Mycobacteria-specific cytokine responses as correlates of treatment response in active and latent tuberculosis

机译：特异性细胞的细胞因子反应作为活性和潜在结核病治疗反应的相关性

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Objectives: A biomarker indicating successful tuberculosis (TB) therapy would assist in determining appropriate length of treatment. This study aimed to determine changes in mycobacteria-specific antigen-induced cytokine biomarkers in patients receiving therapy for latent or active TB, to identify biomarkers potentially correlating with treatment success.

机译：目的：表明成功结核病（TB）治疗的生物标志物将有助于确定适当的治疗长度。本研究旨在确定接受潜在或活性结核病患者的患者的特异性抗原诱导的细胞因子生物标志物的变化，以鉴定潜在与治疗成功相关的生物标志物。

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来源
《Journal of Infection》 |2017年第2期|共14页
作者
Clifford Vanessa; Tebruegge Marc; Zufferey Christel; Germano Susie; Forbes Ben; Cosentino Lucy; McBryde Emma; Eisen Damon; Robins-Browne Roy; Street Alan; Denholm Justin; Curtis Nigel;
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作者单位

Univ Melbourne Dept Paediat Parkville Vic Australia;

Univ Melbourne Dept Paediat Parkville Vic Australia;

Royal Childrens Hosp Melbourne Murdoch Childrens Res Inst Parkville Vic Australia;

Royal Childrens Hosp Melbourne Murdoch Childrens Res Inst Parkville Vic Australia;

Royal Childrens Hosp Melbourne Murdoch Childrens Res Inst Parkville Vic Australia;

Univ Melbourne Dept Microbiol &

Immunol Melbourne Vic Australia;

Royal Melbourne Hosp Victorian Infect Dis Serv Parkville Vic Australia;

Royal Melbourne Hosp Victorian Infect Dis Serv Parkville Vic Australia;

Royal Childrens Hosp Melbourne Murdoch Childrens Res Inst Parkville Vic Australia;

Royal Melbourne Hosp Victorian Infect Dis Serv Parkville Vic Australia;

Univ Melbourne Dept Paediat Parkville Vic Australia;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
Tuberculosis; Cytokines; Biomarkers; Latent TB; Active TB; Monitoring;

机译：结核病;细胞因子;生物标志物;潜伏结核病;活性结核病;监测;

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专利

1. Mycobacteria-specific cytokine responses as correlates of treatment response in active and latent tuberculosis [J] . Clifford Vanessa, Tebruegge Marc, Zufferey Christel, Journal of Infection . 2017,第2期

机译：特异性细胞的细胞因子反应作为活性和潜在结核病治疗反应的相关性
2. Mycobacteria-Specific Cytokine Responses Detect Tuberculosis Infection and Distinguish Latent from Active Tuberculosis [J] . Marc Tebruegge, Binita Dutta, Susan Donath, American journal of respiratory and critical care medicine . 2015,第4期

机译：分枝杆菌特异的细胞因子反应检测结核感染和区分活动性结核的潜能
3. The effect of HIV coinfection, HAART and TB treatment on cytokine/chemokine responses to Mycobacterium tuberculosis (Mtb) antigens in active TB patients and latently Mtb infected individuals [J] . Kassa Desta, de Jager Wilco, Gebremichael Gebremedhin, Tuberculosis . 2016,第1期

机译：HIV合并感染，HAART和TB治疗对活动性TB患者和潜在Mtb感染个体对结核分枝杆菌（Mtb）抗原的细胞因子/趋化因子反应的影响
4. Effect of Environmental Factors on Tuberculosis Patients Treatment Response at Lower Rift Valley, Southern Ethiopia [C] . Adane W. Shana Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：环境因素对埃塞俄比亚南部下裂谷结核病患者治疗反应的影响
5. Structural and Functional Brain Correlates of Treatment Response in Posttraumatic Stress Disorder [D] . Hinojosa, Cecilia Angelica. 2021

机译：结构和功能性脑与术后应激障碍治疗响应的关联
6. Mycobacteria-Specific Mono- and Polyfunctional CD4+ T Cell Profiles in Children With Latent and Active Tuberculosis: A Prospective Proof-of-Concept Study [O] . Marc Tebruegge, Nicole Ritz, Susan Donath, -1

机译：潜伏性和活动性肺结核儿童的分枝杆菌特异性单功能和多功能CD4 + T细胞谱：一项前瞻性概念验证研究
7. Mycobacteria-specific cytokine responses detect tuberculosis infection and distinguish latent from active tuberculosis [O] . Tebruegge, Marc, Dutta, Binita, Donath, Susan, 2015

机译：分枝杆菌特异性细胞因子反应检测结核感染并区分潜伏性和活动性结核病

Mycobacteria-specific cytokine responses as correlates of treatment response in active and latent tuberculosis

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