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We greatly appreciate the interest of Dr. Reek-ers in our recently published study, which is the first one to record and document the actual incidence of macro- and microembolizationduring revascularization procedures of infra-aortic arterial occlusive disease. Although Dr. Reekers expressed some quite interesting views worth discussing further, he slightly misunderstood the overall reported data. As it is explicitly stated in the text and the accompanying tables of the study, filter-protected revascularization was performed in 48 patients by applying 50 filter baskets in total (2 cases necessitated insertion of a second filter due to large thromboemboli). Regarding the captured debris, we reported that macro-scopically visible particles were evident in 94.0% (47/50) of the filters after retrieval. Moreover, particles with a major axis >1 and >3 mm were detected in 58.0% (29/50) and 12.0% (6/50) of the examined baskets, respectively. Thus, one might speculate that the estimated rate of prevented distalembolism was more than double the reported rate in the literature. Arguably, the statistical analysis mainly incriminated declotting procedures for this finding, which is in accordance with worldwide clinical experience.
机译:我们非常感谢Reek-Eds博士在我们最近发表的研究中的兴趣,这是第一个录制和记录宏观和微栓塞血管化程序的实际发生率的血管内发生症的实际发生率。虽然Reekers博士表达了一些非常有趣的观点,值得进一步讨论,但他稍微误解了整体报告的数据。正如在文本中明确说明的那样,通过施加50个过滤器篮总共施加50个过滤器筐,在48名患者中进行过滤的血运重建(2例,因为大血栓均匀,2例需要插入第二滤波器)。关于捕获的碎片,我们报告说,在检索后,在94.0%(47/50)的过滤器中,宏观术可见颗粒明显。此外,分别在58.0%(29/50)和12.0%(6/50)的检查篮中检测具有长轴> 1和> 3mm的颗粒。因此,人们可能推测预防滞后栓塞率的估计率大于文献中报告的率的两倍。可以说,统计分析主要是针对这一发现的令人厌恶的解说程序,这是根据全球临床经验。

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