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Improving Engagement in the HIV Care Cascade: A Systematic Review of Interventions Involving People Living with HIV/AIDS as Peers

机译:加强对艾滋病毒/艾滋病关怀的参与:对涉及艾滋病毒/艾滋病感染者的同行进行干预的系统评价

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摘要

Improving patient engagement in HIV care is critical for maximizing the impact of antiretroviral therapy (ART). We conducted a systematic review of studies that used HIV-positive peers to bolster linkage, retention, and/or adherence to ART. We searched articles published and indexed in Pubmed, PsycINFO, and CINAHL between 1996 and 2014. Peers were required to be HIV-positive. Studies were restricted to those published in English. Nine studies with n = 4658 participants met the inclusion criteria. Peer-based interventions were predominantly focused on improving adherence to ART, or evaluations of retention and adherence via viral suppression. Five (56 %) were conducted in sub-Saharan Africa. Overall findings were mixed on the impact of peers on ART adherence, viral suppression, and mortality. While positive effects of peer interventions on improving linkage and retention were found, there were limited studies assessing these outcomes. Additional research is warranted to demonstrate the impact of peers on linkage and retention in diverse populations.
机译:改善患者对HIV护理的参与度对于最大化抗逆转录病毒疗法(ART)的影响至关重要。我们对使用HIV阳性同伴加强抗病毒治疗的联系,保留和/或依从性的研究进行了系统的回顾。我们搜索了1996年至2014年之间在Pubmed,PsycINFO和CINAHL中发表并建立索引的文章。对等体必须是HIV阳性。研究仅限于以英语发表的研究。 9项研究(n = 4658名参与者)符合纳入标准。基于同伴的干预措施主要集中于改善对ART的依从性,或通过病毒抑制评估保留率和依从性。在撒哈拉以南非洲进行了五次(56%)。关于同龄人对抗逆转录病毒药物依从性,病毒抑制和死亡率的影响,总体研究结果参差不齐。虽然发现同伴干预对改善联系和保留有积极作用,但评估这些结果的研究有限。有必要进行更多的研究来证明同龄人对不同人群的联系和保留的影响。

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