Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn's Disease

Wright Emily K.; Kamm Michael A.; De Cruz Peter; Hamilton Amy L.; Selvaraj Fabiyola; Princen Fred; Gorelik Alexandra; Liew Danny; Prideaux Lani; Lawrance Ian C.; Andrews Jane M.; Bampton Peter A.; Jakobovits Simon L.; Florin Timothy H.; Gibson Peter R.; Debinski Henry; Macrae Finlay A.; Samuel Douglas; Kronborg Ian; Radford-Smith Graham; Gearry Richard B.; Selby Warwick; Bell Sally J.; Brown Steven J.; Connell William R.

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Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn's Disease

机译：术后克罗恩病中抗TNF治疗药物监测

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摘要

Background: Anti-TNF prevents postoperative Crohn's disease recurrence in most patients but not all. This study aimed to define the relationship between adalimumab pharmacokinetics, maintenance of remission and recurrence.

机译：背景：抗TNF在大多数患者中预防术后克罗恩病复发，但并非所有患者。本研究旨在定义阿达罗单抗药代动力学，缓解和复发的维持之间的关系。

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来源
《Journal of Crohn’s & colitis》 |2018年第6期|共9页
作者
Wright Emily K.; Kamm Michael A.; De Cruz Peter; Hamilton Amy L.; Selvaraj Fabiyola; Princen Fred; Gorelik Alexandra; Liew Danny; Prideaux Lani; Lawrance Ian C.; Andrews Jane M.; Bampton Peter A.; Jakobovits Simon L.; Florin Timothy H.; Gibson Peter R.; Debinski Henry; Macrae Finlay A.; Samuel Douglas; Kronborg Ian; Radford-Smith Graham; Gearry Richard B.; Selby Warwick; Bell Sally J.; Brown Steven J.; Connell William R.;
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作者单位

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

Prometheus Labs Inc Dept Res &

Dev San Diego CA USA;

Prometheus Labs Inc Dept Res &

Dev San Diego CA USA;

Univ Melbourne Melbourne EpiCtr Melbourne Vic Australia;

Monash Univ Sch Publ Hlth &

Preventat Med Melbourne Vic Australia;

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

Fremantle Hosp Ctr Inflammatory Bowel Dis Fremantle WA Australia;

Royal Adelaide Hosp Dept Gastroenterol &

Hepatol Adelaide SA Australia;

Flinders Med Ctr Dept Gastroenterol &

Hepatol Adelaide SA Australia;

Alfred Hlth Dept Gastroenterol Melbourne Vic Australia;

Univ Queensland Mater Hlth Serv Dept Gastroenterol Brisbane Qld Australia;

Alfred Hlth Dept Gastroenterol Melbourne Vic Australia;

Cabrini Hosp Melbourne Gastrointestinal Invest Unit Melbourne Vic Australia;

Univ Melbourne Melbourne Vic Australia;

Bankstown Hosp Dept Gastroenterol Sydney NSW Australia;

Western Hosp Dept Gastroenterol Melbourne Vic Australia;

Royal Brisbane &

Womens Hosp Dept Gastroenterol Brisbane Qld Australia;

Univ Otago Dept Med Christchurch New Zealand;

Royal Prince Alfred Hosp AW Morrow Gastroenterol &

Liver Ctr Sydney NSW Australia;

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

St Vincents Hosp Dept Gastroenterol Melbourne Vic Australia;

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原文格式 PDF
正文语种 eng
中图分类杆菌传染病;
关键词
Inflammatory Bowel Disease; adalimumab; anti-TNF; therapeutic drug monitoring;

机译：炎症性肠病;atabalimumab;抗TNF;治疗药物监测;

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专利

1. Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn's Disease [J] . Wright Emily K., Kamm Michael A., De Cruz Peter, Journal of Crohn’s & colitis . 2018,第6期

机译：术后克罗恩病中抗TNF治疗药物监测
2. Therapeutic drug monitoring to improve outcome of anti-TNF drugs in pediatric inflammatory bowel disease [J] . Raffaella Franca, Debora Curci, Marianna Lucafo, Expert opinion on drug metabolism & toxicology . 2019,第7a12期

机译：治疗药物监测改善儿科炎症肠病抗TNF药物的结果
3. Real World Experience in Therapeutic Drug Monitoring in Inflammatory Bowel Disease: Lack of Anti-Drug Antibodies to Vedolizumab and Ustekinumab Compared to Anti-TNF Agents in IBD [J] . Glassner Kerri L., Oglat Ayah, Abraham Bincy The American Journal of Gastroenterology . 2018,第Suppla2期

机译：炎症性肠病治疗药物监测的真实世界经验：与IBD中的抗TNF药剂相比，缺乏对Vedolizumab和Ustekinumab的抗药抗体
4. Anti-TNF strategies in paediatric Crohn's disease [C] . Falk Symposium . 2002

机译：儿科克罗恩病中的抗TNF策略
5. Mononuclear Phagocyte Differentiation Highlights the Role of NOD2 in Stricturing Crohn's Disease, Revealing New Therapeutic Targets [D] . Nayar, Shikha. 2021

机译：单核吞噬细胞分化突出了NOD2在狭窄克罗恩病中的作用，揭示了新的治疗目标
6. UK National Survey of Gastroenterologists’ attitudes and barriers toward therapeutic drug monitoring of anti-TNF therapy in inflammatory bowel disease [O] . Gaurav B Nigam, Shadab Nayeemuddin, Evangelos Kontopantelis, 2021

机译：英国国家胃肠学症患者对炎症性肠病抗TNF治疗治疗药物监测的态度和障碍调查
7. Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn’s Disease [O] . Emily K Wright, Michael A Kamm, Peter De Cruz, 2018

机译：术后克罗恩病中抗TNF治疗药物监测

Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn's Disease

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