Simple strategy for sensitive detection of dopamine using CdTe QD QD s modified glassy carbon electrode

摘要

Background Cellular and brain metabolism of dopamine can be correlated with a number of neurodegenerative disorders, our study was to explore a simple and efficient method to detect dopamine in real samples. Methods A new quantum dots (CdTe QD s) could be prepared using the hydrothermal method, the electrochemical biosensor was established by dropping CdTe QD s on the surface of glassy carbon electrode ( GCE ). Results The CdTe QD s/ GCE exhibited the excellent electrochemical catalytic activity toward dopamine ( DA ) with good stability and high sensitivity in presence of interfering substances. The detection limit of DA was calculated by differential pulse voltammetry ( DPV ) as low as 0.3?μmol L ?1 with a linear dynamic range of 1?μmol L ?1 to 400?μmol L ?1 . Conclusion In this paper, the proposed electrochemical biosensor could be effectively used for the direct and rapid detection of DA in human serum and urine samples.