Development of a liquid dissection technique for small-incision lenticule extraction: Clinical results and ultrastructural evaluation

摘要

PurposeTo determine the effect of a liquid dissection technique on clinical outcomes with ultrastructural analysis of the lenticule surface in small-incision lenticule extraction (SMILE). SettingZhongshan Ophthalmic Center, Guangzhou, China. DesignProspective case series. MethodsConsecutive patients with myopia scheduled for small-incision lenticule extraction were included. The liquid dissection technique was performed in 1 eye and the traditional dissection technique was performed in the other eye by randomized assignment. Ophthalmic examinations were evaluated preoperatively and at different timepoint follow-ups after small-incision lenticule extraction. Ten human corneal lenticules were analyzed using scanning electron microscopy. ResultsThe study comprised 29 patients (58 eyes). Uncorrected distance visual acuity (logarithm of the minimum angle of resolution) postoperative measurements at 2 and 4?hours were significantly better in the liquid dissection group than in the traditional dissection group (P?