Prediction of liver partitioning for compounds that are actively taken up into hepatocytes: measurement in vivo and prediction using in vitro hepatocyte uptake

Zhang Yueping; Sun Hudong; Morse Bridget; Marathe Punit; Humphreys William; Lai Yurong

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Prediction of liver partitioning for compounds that are actively taken up into hepatocytes: measurement in vivo and prediction using in vitro hepatocyte uptake

机译：用于肝细胞的化合物的肝脏分配预测：使用体外肝细胞摄取体内的测量和预测

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来源
《Drug Metabolism Reviews》 |2016年第4期|共1页
作者
Zhang Yueping; Sun Hudong; Morse Bridget; Marathe Punit; Humphreys William; Lai Yurong;
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作者单位

Bristol Myers Squibb Princeton NJ USA;

Bristol Myers Squibb Princeton NJ USA;

Bristol Myers Squibb Princeton NJ USA;

Bristol Myers Squibb Princeton NJ USA;

Bristol Myers Squibb Princeton NJ USA;

Bristol Myers Squibb Princeton NJ USA;

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原文格式 PDF
正文语种 eng
中图分类药理学;
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1. Prediction of liver partitioning for compounds that are actively taken up into hepatocytes: measurement in vivo and prediction using in vitro hepatocyte uptake [J] . Zhang Yueping, Sun Hudong, Morse Bridget, Drug Metabolism Reviews . 2016,第1a4期

机译：用于肝细胞的化合物的肝脏分配预测：使用体外肝细胞摄取体内的测量和预测
2. Prediction of liver partitioning for compounds that are actively taken up into hepatocytes: measurement in vivo and prediction using in vitro hepatocyte uptake [J] . Zhang Yueping, Sun Hudong, Morse Bridget, Drug Metabolism Reviews . 2016,第1a4期

机译：用于肝细胞的化合物的肝脏分配预测：使用体外肝细胞摄取体内的测量和预测
3. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake [J] . Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2015,第11期

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6. Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study [O] . Anne Granitzny, Jan Knebel, Meike Müller, 2014

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Prediction of liver partitioning for compounds that are actively taken up into hepatocytes: measurement in vivo and prediction using in vitro hepatocyte uptake

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