Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

Betteridge Z.; Tansley S.; Shaddick G.; Chinoy H.; Cooper R. G.; New R. P.; Lilleker J. B.; Vencovsky J.; Chazarain L.; Danko K.; Nagy-Vincze M.; Bodoki L.; Dastmalchi M.; Ekholm L.; Lundberg I. E.; McHugh N.; Mann Herman; Krystufkova Olga; Klein Martin; Barochova Tereza; Kubinova Katerina; Lamb Janine; Rothwell Simon; Ahmed Yasmeen; Armstrong Raymond; Bernstein Robert; Black Carol; Bowman Simon; Bruce Ian; Butler Robin; Carty John; Chattopadhyay Chandra; Chelliah Easwaradhas; Clarke Fiona; Dawes Peter; Denton Christopher; Devlin Joseph; Edwards Christopher; Emery Paul; Fordham John; Fraser Alexander; Gaston Hill; Gordon Patrick; Griffiths Bridget; Gunawardena Harsha; Hall Frances; Hanna Michael; Harrison Beverley; Hay Elaine; Hilton-Jones David; Horden Lesley; Isaacs John; Isenberg David; Jones Adrian; Kamath Sanjeet; Kennedy Thomas; Kitas George; Klimiuk Peter; Knights Sally; Lambert John; Lanyon Peter; Laxminarayan Ramasharan; Lecky Bryan; Luqmani Raashid; Machado Pedro; Marks Jeffrey; Martin Michael; McGonagle Dennis; McKenna Francis; McLaren John; McMahon Michael; McRorie Euan; Merry Peter; Miles Sarah; Miller James; Nicholls Anne; Nixon Jennifer; Ong Voon; Over Katherine; Packham John; Pipitone Nicolo; Plant Michael; Pountain Gillian; Pullar Thomas; Roberts Mark; Sanders Paul; Scott David; Shadforth Michael; Sheeran Thomas; Srinivasan Arul; Swinson David; Teh Lee-Suan; Webley Michael; Williams Brian; Winer Jonathan

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Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

机译：肌炎自身抗体在欧洲成本炎症肌病患者组合群组中的频率，互联性和临床关联

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Objectives: To determine prevalence and co-existence of myositis specific autoantibodies (MSAs) and myositis associated autoantibodies (MAAs) and associated clinical characteristics in a large cohort of idiopathic inflammatory myopathy (IIM) patients.

机译：目的：确定肌炎特异性自身抗体（MSAS）和肌炎相关的自身抗体（MAAS）的患病率和共存，以及在大型特发性炎症肌病（IIM）患者中的相关临床特征。

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《Journal of Autoimmunity》 |2019年第2019期|共8页
作者
Betteridge Z.; Tansley S.; Shaddick G.; Chinoy H.; Cooper R. G.; New R. P.; Lilleker J. B.; Vencovsky J.; Chazarain L.; Danko K.; Nagy-Vincze M.; Bodoki L.; Dastmalchi M.; Ekholm L.; Lundberg I. E.; McHugh N.; Mann Herman; Krystufkova Olga; Klein Martin; Barochova Tereza; Kubinova Katerina; Lamb Janine; Rothwell Simon; Ahmed Yasmeen; Armstrong Raymond; Bernstein Robert; Black Carol; Bowman Simon; Bruce Ian; Butler Robin; Carty John; Chattopadhyay Chandra; Chelliah Easwaradhas; Clarke Fiona; Dawes Peter; Denton Christopher; Devlin Joseph; Edwards Christopher; Emery Paul; Fordham John; Fraser Alexander; Gaston Hill; Gordon Patrick; Griffiths Bridget; Gunawardena Harsha; Hall Frances; Hanna Michael; Harrison Beverley; Hay Elaine; Hilton-Jones David; Horden Lesley; Isaacs John; Isenberg David; Jones Adrian; Kamath Sanjeet; Kennedy Thomas; Kitas George; Klimiuk Peter; Knights Sally; Lambert John; Lanyon Peter; Laxminarayan Ramasharan; Lecky Bryan; Luqmani Raashid; Machado Pedro; Marks Jeffrey; Martin Michael; McGonagle Dennis; McKenna Francis; McLaren John; McMahon Michael; McRorie Euan; Merry Peter; Miles Sarah; Miller James; Nicholls Anne; Nixon Jennifer; Ong Voon; Over Katherine; Packham John; Pipitone Nicolo; Plant Michael; Pountain Gillian; Pullar Thomas; Roberts Mark; Sanders Paul; Scott David; Shadforth Michael; Sheeran Thomas; Srinivasan Arul; Swinson David; Teh Lee-Suan; Webley Michael; Williams Brian; Winer Jonathan;
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作者单位

Univ Bath Dept Pharm &

Pharmacol Bath Avon England;

Univ Bath Dept Pharm &

Pharmacol Bath Avon England;

Univ Exeter Dept Math Exeter Devon England;

Univ Manchester Manchester Acad Hlth Sci Ctr Ctr Musculoskeletal Res Manchester Lancs England;

Univ Liverpool Inst Ageing &

Chron Dis Liverpool Merseyside England;

Univ Liverpool Inst Ageing &

Chron Dis Liverpool Merseyside England;

Univ Manchester Manchester Acad Hlth Sci Ctr Ctr Musculoskeletal Res Manchester Lancs England;

Charles Univ Prague Inst Rheumatol Med Fac 1 Prague Czech Republic;

Charles Univ Prague Inst Rheumatol Med Fac 1 Prague Czech Republic;

Univ Debrecen Dept Internal Med Debrecen Hungary;

Univ Debrecen Dept Internal Med Debrecen Hungary;

Univ Debrecen Dept Internal Med Debrecen Hungary;

Solna Karolinska Inst Div Rheumatol Dept Med Stockholm Sweden;

Solna Karolinska Inst Div Rheumatol Dept Med Stockholm Sweden;

Solna Karolinska Inst Div Rheumatol Dept Med Stockholm Sweden;

Univ Bath Dept Pharm &

Pharmacol Bath Avon England;

Inst Rheumatol Prague Czech Republic;

Inst Rheumatol Prague Czech Republic;

Inst Rheumatol Prague Czech Republic;

Inst Rheumatol Prague Czech Republic;

Inst Rheumatol Prague Czech Republic;

Univ Manchester Manchester Lancs England;

Univ Manchester Manchester Lancs England;

Llandudno Gen Hosp Llandudno Wales;

Southampton Gen Hosp Southampton Hants England;

Manchester Royal Infirm Manchester Lancs England;

Royal Free Hosp London England;

Univ Hosp Birmingham W Midlands England;

Manchester Royal Infirm Manchester Lancs England;

Robert Jones &

Agnes Hunt Orthopaed Hosp Oswestry Shrops England;

Lincoln Cty Hosp Lincoln England;

Wrightington Hosp Wigan England;

Wrightington Hosp Wigan England;

James Cook Univ Hosp Middlesbrough England;

Staffordshire Rheumatol Ctr Stoke On Trent Staffs England;

Royal Free London London England;

Pinderfields Gen Hosp Wakefield England;

Southampton Gen Hosp Southampton Hants England;

Acad Unit Musculoskeletal Dis Leeds W Yorkshire England;

South Cleveland Hosp Middlesbrough England;

Acad Unit Musculoskeletal Dis Leeds W Yorkshire England;

Addenbrookes Hosp Cambridge England;

Kings Coll Hosp London London England;

Freeman Rd Hosp Newcastle England;

Frenchay Hosp Bristol Avon England;

Addenbrookes Hosp Cambridge England;

Univ Coll London Hosp London England;

North Manchester Gen Hosp Manchester Lancs England;

Staffordshire Rheumatol Ctr Stoke On Trent Staffs England;

Oxford Univ Hosp Oxford England;

Dewsbury Dist Gen Hosp Dewsbury England;

Freeman Rd Hosp Newcastle England;

Univ Coll London Hosp London England;

Nottingham Univ Hosp Nottingham England;

Staffordshire Rheumatol Ctr Stoke On Trent Staffs England;

Royal Liverpool Hosp Liverpool Merseyside England;

Dudley Grp Hosp Trust Birmingham W Midlands England;

Royal Oldham Hosp Oldham England;

Yeovil Dist Hosp Somerset NJ USA;

Doncaster Royal Infirm Doncaster England;

Queens Med Ctr Nottingham England;

Queens Hosp Burton Upon Trent England;

Walton Neurosci Ctr Liverpool Merseyside England;

Nuffield Orthopaed Ctr Oxford England;

Univ Coll London Hosp London England;

Steeping Hill Hosp Stockport Lancs England;

St James Univ Hosp Leeds W Yorkshire England;

Acad Unit Musculoskeletal Dis Leeds W Yorkshire England;

Trafford Gen Hosp Manchester Lancs England;

Cameron Hosp Leven Fife Scotland;

Dumfries &

Galloway Royal Infirm Dumfries Scotland;

Western Gen Hosp Edinburgh Midlothian Scotland;

Norfolk &

Norwich Univ Hosp Norwich Norfolk England;

Dewsbury &

Dist Gen Hosp Dewsbury England;

Royal Victoria Hosp Newcastle England;

West Suffolk Hosp Bury St Edmunds Suffolk England;

Countess Chester Hosp Chester Cheshire England;

Royal Free Hosp London England;

Countess Chester Hosp Chester Cheshire England;

Staffordshire Rheumatol Ctr Stoke On Trent Staffs England;

Kings Coll Hosp London London England;

South Cleveland Hosp Middlesbrough England;

Hinchingbrooke Hosp Huntington England;

Ninewells Hosp Dundee Scotland;

Salford Royal Fdn Trust Salford Lancs England;

Wythenshawe Hosp Manchester Lancs England;

Kings Coll Hosp London London England;

Staffordshire Rheumatol Ctr Stoke On Trent Staffs England;

Cannock Chase Hosp Cannock Staffs England;

Broomfield Hosp Chelmsford Essex England;

Wrightington Hosp Wigan England;

Royal Blackburn Hosp Blackburn Lancs England;

Stoke Manderville Hosp Aylesbury Bucks England;

Univ Hosp Wales Cardiff S Glam Wales;

Queen Elizabeth Hosp Birmingham W Midlands England;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Myositis; Dermatomyositis; Polymyositis; Autoantibodies; Autoimmune;

机译：肌炎;Dermatomyositis;polyalyositis;自身抗体;自身免疫;

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外文文献
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专利

1. Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients [J] . Betteridge Z., Tansley S., Shaddick G., Journal of Autoimmunity . 2019,第期

机译：肌炎自身抗体在欧洲成本炎症肌病患者组合群组中的频率，互联性和临床关联
2. Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features [J] . Yasin S. A., Schutz P. W., Deakin C. T., Neuropathology and applied neurobiology . 2019,第5期

机译：大型特发性炎症性肌病的大临床群体中的组织学异质性：肌炎自身抗体和病理特征分析
3. Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies. [J] . OHanlon TP, Carrick DM, Targoff IN, Medicine. . 2006,第2期

机译：特发性炎症性肌病的免疫遗传风险和保护因素：独特的HLA-A，-B，-Cw，-DRB1和-DQA1等位基因特征可区分具有不同肌炎自身抗体的欧美患者。
4. Defining Clinical and Autoantibody Phenotypes in Patients with Juvenile Idiopathic Inflammatory Myopathies. [D] . Shah, Mona N. 2012

机译：定义青少年特发性炎症性肌病患者的临床和自身抗体表型。
5. Frequency mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients [O] . Z. Betteridge, S. Tansley, G. Shaddick, -1

机译：欧洲特发性炎性肌病患者合并症中肌炎自身抗体的频率互斥性和临床关联
6. Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients [O] . Z. Betteridge, S. Tansley, G. Shaddick, 2019

机译：肌炎自身抗体在欧洲成交炎症肌病患者组合群组中的频率，互联性和临床关联

Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

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