Sleep disturbance may impact treatment outcome in bipolar disorder: A preliminary investigation in the context of a large comparative e?ectiveness trial

摘要

Bipolar disorder is a chronic condition characterized by episodes of mania or hypomania and depression. These episodes typically include sleep disturbance (i.e., lack of sleep, insomnia, or excessive sleep), making sleep disturbance a core feature of bipolar disorder (American Psychiatric Association, 2013).