Association of White Matter With Core Cognitive Deficits in Patients With Schizophrenia

Kochunov Peter; Coyle Thomas R.; Rowland Laura M.; Jahanshad Neda; Thompson Paul M.; Kelly Sinead; Du Xiaoming; Sampath Hemalatha; Bruce Heather; Chiappelli Joshua; Ryan Meghann; Fisseha Feven; Savransky Anya; Adhikari Bhim; Chen Shuo; Paciga Sara A.; Whelan Christopher D.; Xie Zhiyong; Hyde Craig L.; Chen Xing; Schubert Christian R.; ODonnell Patricio; Hong L. Elliot

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Association of White Matter With Core Cognitive Deficits in Patients With Schizophrenia

机译：白金与精神分裂症患者核心认知缺陷的关联

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摘要

IMPORTANCE Efforts to remediate the multiple cognitive function impairments in schizophrenia should consider white matter as one of the underlying neural mechanisms.

机译：在精神分裂症中修复多重认知功能障碍的重要努力应将白质视为潜在的神经机制之一。

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《JAMA psychiatry》 |2017年第9期|共9页
作者
Kochunov Peter; Coyle Thomas R.; Rowland Laura M.; Jahanshad Neda; Thompson Paul M.; Kelly Sinead; Du Xiaoming; Sampath Hemalatha; Bruce Heather; Chiappelli Joshua; Ryan Meghann; Fisseha Feven; Savransky Anya; Adhikari Bhim; Chen Shuo; Paciga Sara A.; Whelan Christopher D.; Xie Zhiyong; Hyde Craig L.; Chen Xing; Schubert Christian R.; ODonnell Patricio; Hong L. Elliot;
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作者单位

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Texas San Antonio Dept Psychol San Antonio TX USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Southern Calif Keck Sch Med Imaging Genet Ctr Marina Del Rey CA USA;

Univ Southern Calif Keck Sch Med Imaging Genet Ctr Marina Del Rey CA USA;

Univ Southern Calif Keck Sch Med Imaging Genet Ctr Marina Del Rey CA USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

Pfizer Inc Worldwide Res &

Dev Cambridge MA USA;

Pfizer Inc Worldwide Res &

Dev Cambridge MA USA;

Pfizer Inc Worldwide Res &

Dev Cambridge MA USA;

Pfizer Inc Worldwide Res &

Dev Cambridge MA USA;

Pfizer Inc Worldwide Res &

Dev Cambridge MA USA;

Biogen Cambridge MA USA;

Pfizer Inc Worldwide Res &

Dev Cambridge MA USA;

Univ Maryland Sch Med Dept Psychiat Maryland Psychiat Res Ctr Baltimore MD 21228 USA;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
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专利

1. Association of White Matter With Core Cognitive Deficits in Patients With Schizophrenia [J] . Kochunov Peter, Coyle Thomas R., Rowland Laura M., JAMA psychiatry . 2017,第9期

机译：白金与精神分裂症患者核心认知缺陷的关联
2. Cognitive deficits and white matter abnormalities in never-treated first-episode schizophrenia [J] . Mi Yang, Shan Gao, Xiangyang Zhang Translational psychiatry. . 2020,第1期

机译：从未治疗的首发精神分裂症中的认知赤字和白质异常
3. Reduced white matter integrity and cognitive deficit in never-medicated chronic schizophrenia: A diffusion tensor study using TBSS [J] . LiuX., LaiY., WangX., Behavioural Brain Research: An International Journal . 2013,第Null期

机译：从未用药的慢性精神分裂症患者白质完整性和认知功能障碍的减少：使用TBSS的扩散张量研究
4. Small world network measures predict white matter degeneration in patients with early-stage mild cognitive impairment [C] . Nir Talia, Jahanshad Neda, Jack Clifford R., Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on . 2012

机译：小型世界网络量度可预测患有早期轻度认知障碍的患者的白质退化
5. Striatal Activity is Associated with Deficits of Cognitive Control and Aberrant Salience for Patients with Schizophrenia [D] . Ceaser, Alan Edward 2015

机译：纹状体活动与精神分裂症患者的认知控制和异常显着性缺乏相关。
6. Associations Among Suicidal Ideation White Matter Integrity and Cognitive Deficit in First-Episode Schizophrenia [O] . Yicheng Long, Xuan Ouyang, Zhening Liu, 2018

机译：首发精神分裂症患者的自杀意念白色物质完整性和认知缺陷之间的关联
7. Associations Among Suicidal Ideation, White Matter Integrity and Cognitive Deficit in First-Episode Schizophrenia [O] . Yicheng Long, Xuan Ouyang, Zhening Liu, 2018

机译：在精神分裂症中的自杀意念，白质诚信和认知赤字之间的关联

Association of White Matter With Core Cognitive Deficits in Patients With Schizophrenia

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