EFFICIENT SYNTHESIS OF SOME NEW 1,3,4-THIADIAZOLE AND THIAZOLE DERIVATIVES VIA THIOSEMICARBAZONE DERIVATIVES

摘要

We reported here reactions of hydrazinecarbodithioate and hydrazinecarbothioamide derivatives with hydrazonoyl chloride derivatives to afford 1,3,4-thiadiazole and thiazole derivatives, respectively. Also, reactions of hydrazinecarbothioamide derivatives with alpha-halo esters derivatives, diethyl acetylenedicarboxylate and chloroacetonitrile afforded thiazole derivatives. The structures of the newly synthesized compounds were established based on its elemental analyses and spectral data.