Association of Optical Coherence Tomography Angiography Metrics With Detection of Impaired Macular Microvasculature and Decreased Vision in Amblyopic Eyes The Hong Kong Children Eye Study

摘要

Question Are macular microvascular abnormalities in children with amblyopia still present after adjusting for all known confounders and do they correlate with visual acuity? Findings In this population-based nested case-control study of 30 children with amblyopia and 1045 controls, amblyopic eyes had abnormal macular microvascular represented by decreased foveal avascular zone circularity, decreased fractal dimension, and increased vessel diameter index. LogMAR visual acuity correlated with foveal avascular zone circularity and vessel diameter index. Meaning Quantitative optical coherence tomography angiography metrics detect impaired microvasculature in amblyopic eyes that correlates with visual acuity, suggesting a potential role in amblyopia assessment.