Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV A Randomized Clinical Trial

Gopalan Narendran; Santhanakrishnan Ramesh Kumar; Palaniappan Alangudi Natarajan; Menon Pradeep Aravindan; Lakshman Sekar; Chandrasekaran Padmapriyadarsini; Sivaramakrishnan Gomathi Narayan; Reddy Devarajulu; Kannabiran Bhavani Perumal; Agiboth Hemanth Kumar Kupparam; Krishnamoorthy Vijay; Rathinam Sridhar; Chockalingam Chandrasekar; Manoharan Tamizhselvan; Ayyamperumal MahilMaran; Jayanthi Nalini; Satagopan Kumar; Narayanan Ravichandran; Krishnaraja Raja; Sathiyavelu Sekar; Kesavamurthy Bhanu; Suresh Chandra; Selvachitiram Murugesan; Arasan Gunasundari; Susaimuthu Stella; Rathinam Prabhakaran; Angamuthu Prabhakar; Jayabal Lavanya; Murali Lakshmi; Ramachandran Ranjani; Tripathy Srikanth Prasad; Swaminathan Soumya

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Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV A Randomized Clinical Trial

机译：每日VS患者肺结核患者肺结核的间歇性抗结核疗法患者随机临床试验

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摘要

IMPORTANCE The benefit of daily over thrice-weekly antituberculosis therapy among HIV-positive patients with pulmonary tuberculosis (TB) who are receiving antiretroviral therapy remains unproven.

机译：重要性在接受抗逆转录病毒治疗的肺结核患者（TB）的艾滋病毒阳性患者中每日过度接受每周抗性抗尿嘧啶治疗的好处仍未证实。

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《JAMA internal medicine》 |2018年第4期|共9页
作者
Gopalan Narendran; Santhanakrishnan Ramesh Kumar; Palaniappan Alangudi Natarajan; Menon Pradeep Aravindan; Lakshman Sekar; Chandrasekaran Padmapriyadarsini; Sivaramakrishnan Gomathi Narayan; Reddy Devarajulu; Kannabiran Bhavani Perumal; Agiboth Hemanth Kumar Kupparam; Krishnamoorthy Vijay; Rathinam Sridhar; Chockalingam Chandrasekar; Manoharan Tamizhselvan; Ayyamperumal MahilMaran; Jayanthi Nalini; Satagopan Kumar; Narayanan Ravichandran; Krishnaraja Raja; Sathiyavelu Sekar; Kesavamurthy Bhanu; Suresh Chandra; Selvachitiram Murugesan; Arasan Gunasundari; Susaimuthu Stella; Rathinam Prabhakaran; Angamuthu Prabhakar; Jayabal Lavanya; Murali Lakshmi; Ramachandran Ranjani; Tripathy Srikanth Prasad; Swaminathan Soumya;
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作者单位

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Stanley Med Coll Madras Tamil Nadu India;

Govt Hosp Thorac Med TB Sanat Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Madras Med Coll &

Govt Gen Hosp Madras Tamil Nadu India;

Govt Thiruvoteeswrar Hosp Madras Tamil Nadu India;

Govt Hosp Thorac Med TB Sanat Madras Tamil Nadu India;

Govt Hosp Thorac Med TB Sanat Madras Tamil Nadu India;

Govt Hosp Thorac Med TB Sanat Madras Tamil Nadu India;

Madras Med Coll &

Govt Gen Hosp Madras Tamil Nadu India;

Madras Med Coll &

Govt Gen Hosp Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Natl Inst Res TB Madras Tamil Nadu India;

Govt Rajaji Hosp Madurai Tamil Nadu India;

Govt Vellore Med Coll &

Hosp Vellore Tamil Nadu India;

Med Serv TB Vellore Tamil Nadu India;

WHO South East Asian Reg Off New Delhi India;

Natl Inst Res TB Madras Tamil Nadu India;

Indian Council Med Res &

Hlth Res New Delhi India;

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正文语种 eng
中图分类预防医学、卫生学;
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1. Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV A Randomized Clinical Trial [J] . Gopalan Narendran, Santhanakrishnan Ramesh Kumar, Palaniappan Alangudi Natarajan, JAMA internal medicine . 2018,第4期

机译：每日VS患者肺结核患者肺结核的间歇性抗结核疗法患者随机临床试验
2. Optimal Duration of Daily Antituberculosis Therapy before Switching to DOTS Intermittent Therapy to Reduce Mortality in HIV Infected Patients: A Duration-Response Analysis Using Restricted Cubic Splines [J] . GerardoAlvarez-Uria, RaghavakalyanPakam, ManoranjanMidde, International Scholarly Research Notices . 2014,第6期

机译：改用DOTS间歇治疗以降低HIV感染患者的死亡率之前的每日抗结核治疗的最佳持续时间：使用受限三次样条的持续时间响应分析
3. Directly-Observed Intermittent Therapy versus Unsupervised Daily Regimen during the Intensive Phase of Antituberculosis Therapy in HIV Infected Patients [J] . GerardoAlvarez-Uria, ManoranjanMidde, RaghavakalyanPakam, BioMed research international . 2014,第2期

机译：HIV感染患者抗结核治疗强化阶段的直接观察间歇治疗与无监督每日治疗
4. Cluster analysis in assessing the interdependencies of clinical and morphological parameters of patients with mixed infections (pulmonary tuberculosis, chronic viral hepatitis, HIV infection) and heroin addiction [C] . Pigul Evgeniia Yu, Filimonova Galina F., Tokin Ivan B., 2015 International Conference "Stability and Control Processes" in Memory of V.I. Zubov . 2015

机译：聚类分析评估混合感染（肺结核，慢性病毒性肝炎，HIV感染）和海洛因成瘾患者临床和形态学参数之间的相互依赖性
5. Cluster randomized intervention trial to evaluate the impact of the 'opt-out' versus 'opt-in' strategy on the uptake of HIV counseling and testing of tuberculosis patients in the Province of the Eastern Cape, South Africa. [D] . Pope, Diana Spies. 2007

机译：在南非东开普省进行的一项分组随机干预试验，评估了“选择退出”与“选择加入”策略对艾滋病毒咨询和结核病患者检测的接受程度。
6. Evaluation of metformin in combination with rifampicin containing antituberculosis therapy in patients with new smear-positive pulmonary tuberculosis (METRIF): study protocol for a randomised clinical trial [O] . Chandrasekaran Padmapriyadarsini, Perumal K Bhavani, Mohan Natrajan, 2019

机译：二甲双胍联合利福平抗结核治疗对新型涂阳肺结核患者的评估：一项随机临床试验的研究方案
7. Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV [O] . Narendran Gopalan, Ramesh Kumar Santhanakrishnan, Alangudi Natarajan Palaniappan, 2018

机译：每日对艾滋病毒患者肺结核的间歇性抗结核疗法

Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV A Randomized Clinical Trial

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