Base the short-term use of ibuprofen in infants aged 3–6?months on body weight and administer via the oral route if possible

摘要

Ibuprofen is the NSAID most commonly used to treat mild-moderate pain, fever and inflammation in children, although dosage recommendations in infants aged 3–6?months still differ between countries. Based on the available evidence, the short-term use of ibuprofen to manage pain and fever appears to be effective and safe in infants aged 3–6?months who weigh ≥?5–6?kg. The dosage should be weight-based, with preference given to oral preparations. To minimize the risk of renal toxicity, it is important to ensure than the infant is adequately hydrated.