Exploring the characteristics of suboptimally controlled patients after 24 weeks of basal insulin treatment: An individualized approach to intensification

Khunti Kamlesh; Damci Taner; Husemoen Lise Lotte; Babu Vinay; Liebl Andreas

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Exploring the characteristics of suboptimally controlled patients after 24 weeks of basal insulin treatment: An individualized approach to intensification

机译：在基础胰岛素治疗24周后探讨潜水患者的特点：一种强化的个性化方法

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摘要

Aim: To identify characteristics of suboptimally controlled patients with type 2 diabetes (T2DM) on basal insulin treatment who may benefit from intensive titration or further intensification of treatment.

机译：目的：鉴定患有2型糖尿病患者（T2DM）的潜水患者的特点，胰岛素治疗可能受益于密集滴定或进一步加剧治疗。

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来源
《Diabetes research and clinical practice》 |2017年第2017期|共9页
作者
Khunti Kamlesh; Damci Taner; Husemoen Lise Lotte; Babu Vinay; Liebl Andreas;
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作者单位

Univ Leicester Diabet Res Ctr Leicester Leics England;

Istanbul Univ Cerrahpasa Med Sch Dept Endocrinol Diabet &

Metab TR-34363 Istanbul Turkey;

Novo Nordisk AS Soborg Denmark;

Novo Nordisk AS Soborg Denmark;

M&

I Fachklin Bad Heilbrunn Ctr Diabet &

Metab Wornerweg 30 D-83670 Bad Heilbrunn Germany;

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正文语种 eng
中图分类内分泌腺疾病及代谢病;
关键词
Basal insulin detemir; Type 2 diabetes mellitus; HbA1c; Hypoglycemia;

机译：基础胰岛素DECIMIR;2型糖尿病;HBA1C;低血糖;

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专利

1. Exploring the characteristics of suboptimally controlled patients after 24 weeks of basal insulin treatment: An individualized approach to intensification [J] . Khunti Kamlesh, Damci Taner, Husemoen Lise Lotte, Diabetes research and clinical practice . 2017,第期

机译：在基础胰岛素治疗24周后探讨潜水患者的特点：一种强化的个性化方法
2. Efficacy and safety of basal insulin glargine 12 and 24 weeks after initiation in persons with type 2 diabetes: A pooled analysis of data from treatment arms of 15 treat-to-target randomised controlled trials [J] . Owens David R., Traylor Louise, Dain Marie-Paule, Diabetes research and clinical practice . 2014,第2期

机译：基础型甘精胰岛素在开始治疗后12和24周对2型糖尿病患者的疗效和安全性：15项以治疗为目标的随机对照试验的治疗组数据汇总分析
3. Randomized, Open-Label, Parallel-Group Evaluations of Basal-Bolus Therapy Versus Insulin Lispro Premixed Therapy in Patients With Type 2 Diabetes Mellitus Failing to Achieve Control With Starter Insulin Treatment and Continuing Oral Antihyperglycemic Drugs: A Noninferiority Intensification Substudy of the DURABLE Trial* [J] . William F. Miser Richard Arakaki Honghuajiang, Jamie Seism Bacon, Pamela W. Anderson, Clinical therapeutics . 2010,第5期

机译：2型糖尿病患者无法通过入门胰岛素治疗和持续口服降糖药实现控制的基础，基本疗法与胰岛素Lispro预混疗法的随机，开放标签，平行组评估：DUR的非劣效性研究
4. Switching to insulin glargine 300 U/mL from other basal insulin analogues provides less 24-hour glucose variability in hospitalized patients with type 1 diabetes [C] . V.V. Klimontov, E.A. Koroleva, O.N. Fazullina International Multiconference Bioinformatics of Genome Regulation and StructureSystems Biology . 2018

机译：从其他基础胰岛素类似物转换为甘精胰岛素300 U / mL可使住院的1型糖尿病患者的24小时葡萄糖变异性降低
5. Individualized treatments for patients with advanced non-small cell lung cancer: A genetic approach [D] . Ferrao, Amanda. 2013

机译：晚期非小细胞肺癌患者的个体化治疗：一种遗传方法
6. More patients reach glycaemic control with a fixed‐ratio combination of insulin glargine and lixisenatide (iGlarLixi) than with basal insulin at 12 weeks of treatment: A post hoc time‐to‐control analysis of LixiLan‐O and LixiLan‐L [O] . Juan Frias, Manuel Puig Domingo, Luigi Meneghini, -1

机译：在治疗12周时使用固定比例的甘精胰岛素和利西拉来（iGlarLixi）组合进行血糖控制的患者要多于基础胰岛素：进行LixiLan-O和LixiLan-L的事后时间控制分析
7. Exploring the characteristics of suboptimally controlled patients after 24 weeks of basal insulin treatment: An individualized approach to intensification [O] . Khunti, Kamlesh, Damci, Taner, Husemoen, Lise Lotte, 2016

机译：探索基础胰岛素治疗24周后控制欠佳的患者的特征：强化的个性化方法

Exploring the characteristics of suboptimally controlled patients after 24 weeks of basal insulin treatment: An individualized approach to intensification

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