Current treatment of systemic scleroderma

摘要

Systemic sclerosis (scleroderma) is asevere, chronic inflammatory connective tissue disease involving the skin, musculoskeletal system, and several internal organs. The heterogeneity of its presentation and course are aparticular challenge for the treating physician. As therapeutic options have improved considerably during recent years, various working groups have published consensus recommendations for the treatment of SSc. The aim of this overview is to present major aspects of these recommendations and embed them in aconcept of modern interdisciplinary care for this often still devastating disease.