Follicle stimulating hormone versus clomiphene citrate in intrauterine insemination for unexplained subfertility: a randomized controlled trial

Danhof N. A.; van Wely M.; Repping S.; Koks C.; Verhoeve H. R.; de Bruin J. P.; Verberg M. F. G.; van Hooff M. H. A.; Cohlen B. J.; van Heteren C. F.; Fleischer K.; Gianotten J.; van Disseldorp J.; Visser J.; Broekmans F. J. M.; Mol B. W. J.; van der Veen F.; Mochtar M. H.

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Follicle stimulating hormone versus clomiphene citrate in intrauterine insemination for unexplained subfertility: a randomized controlled trial

机译：卵泡刺激激素与克里芬柠檬酸盐，宫内生精中的未解释的肺精剂：随机对照试验

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STUDY QUESTION: Is FSH or clomiphene citrate (CC) the most effective stimulation regimen in terms of ongoing pregnancies in couples with unexplained subfertility undergoing IUI with adherence to strict cancellation criteria as a measure to reduce the number of multiple pregnancies?

机译：研究问题：FSH或Clomiphene柠檬酸盐（CC）在夫妻伴随着未解释的患者的患者中获得最有效的刺激方案，并遵守严格的取消标准作为减少多次怀孕人数的措施？

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《Human Reproduction》 |2018年第10期|共9页
作者
Danhof N. A.; van Wely M.; Repping S.; Koks C.; Verhoeve H. R.; de Bruin J. P.; Verberg M. F. G.; van Hooff M. H. A.; Cohlen B. J.; van Heteren C. F.; Fleischer K.; Gianotten J.; van Disseldorp J.; Visser J.; Broekmans F. J. M.; Mol B. W. J.; van der Veen F.; Mochtar M. H.;
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作者单位

Acad Med Ctr Ctr Reprod Med Meiberg Dreef 9 NL-1105 AZ Amsterdam Netherlands;

Acad Med Ctr Ctr Reprod Med Meiberg Dreef 9 NL-1105 AZ Amsterdam Netherlands;

Acad Med Ctr Ctr Reprod Med Meiberg Dreef 9 NL-1105 AZ Amsterdam Netherlands;

Maxima Med Ctr Dept Obstet &

Gynaecol Postbus 7777 NL-5500 MB Veldhoven Netherlands;

OLVG Oost Dept Obstet &

Gynaecol Oosterpk 9 NL-1091 AC Amsterdam Netherlands;

Jeroen Bosch Hosp Dept Obstet &

Gynecol Postbus 90153 NL-5200 ME Shertogenbosch Netherlands;

Fertil Clin Twente Demmersweg 66 NL-7556 BN Hengelo Netherlands;

St Franciscus Gasthuis Dept Obstet &

Gynaecol Kleiweg 500 NL-3045 PM Rotterdam Netherlands;

Isala Hosp Dept Obstet &

Gynecol Postbus 10400 NL-8000 GK Zwolle Netherlands;

Canisius Wilhelmina Hosp Dept Obstet &

Gynaecol Postbus 9015 NL-6500 GS Nijmegen Netherlands;

Radboud Univ Nijmegen Med Ctr Ctr Reprod Med Geert Grootepl Zuid 10 NL-6525 GA Nijmegen;

Spaarne Gasthuis Dept Obstet &

Gynaecol Postbus 417 NL-2000 AK Haarlem Netherlands;

St Antonius Hosp Nieuwegein Dept Obstet &

Gynaecol Koekoekslaan 1 NL-3435 CM Nieuwegein;

Dept Obstet &

Gynaecol Amphia Postbus 90157 NL-4800 RL Breda Netherlands;

Univ Med Ctr Utrecht Ctr Reprod Med Postbus 85500 NL-3508 GA Utrecht Netherlands;

Monash Univ Monash Med Ctr 246 Clayton Rd Clayton Vic 3168 Australia;

Acad Med Ctr Ctr Reprod Med Meiberg Dreef 9 NL-1105 AZ Amsterdam Netherlands;

Acad Med Ctr Ctr Reprod Med Meiberg Dreef 9 NL-1105 AZ Amsterdam Netherlands;

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原文格式 PDF
正文语种 eng
中图分类人体生理学;
关键词
IUI; ovarian stimulation; FSH; clomiphene citrate; unexplained subfertility; cancellation criteria;

机译：IUI;卵巢刺激;FSH;Clomiphenhenhenhene柠檬酸盐;未解释的化学生;取消标准;

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专利

1. Follicle stimulating hormone versus clomiphene citrate in intrauterine insemination for unexplained subfertility: a randomized controlled trial [J] . Danhof N. A., van Wely M., Repping S., Human Reproduction . 2018,第10期

机译：卵泡刺激激素与克里芬柠檬酸盐，宫内生精中的未解释的肺精剂：随机对照试验
2. Recombinant FSH versus clomiphene citrate for ovarian stimulation in couples with unexplained infertility and male subfertility undergoing intrauterine insemination: a randomized trial. [J] . Berker B, Kahraman K, Taskin S, Archives of gynecology and obstetrics. . 2011,第6期

机译：重组FSH与枸clo酸克罗米酚在无法解释的不育症和接受子宫内授精的男性不育症夫妇的卵巢刺激中：一项随机试验。
3. Recombinant FSH versus clomiphene citrate for ovarian stimulation in couples with unexplained infertility and male subfertility undergoing intrauterine insemination: a randomized trial [J] . Bulent Berker, Korhan Kahraman, Salih Taskin, Archives of Gynecology and Obstetrics . 2011,第6期

机译：重组FSH与枸clo酸克罗米芬对不明原因的不孕症和接受子宫内授精的男性不育症夫妇的卵巢刺激：一项随机试验
4. Retrospective study of human chorionic gonadotrophin-induced ovulation versus urinary luteinizing hormone surge detection for timing of intrauterine insemination [C] . R. Hirata, T. Habara, N. Hayashi World Congress on Fertility and Sterility . 2004

机译：人绒毛膜促性腺激素诱导的排卵对尿黄素诱导肠呆子授精定时的回顾性研究
5. A randomized, double-blind, placebo-controlled phase II trial to examine the effect of polyphenon E on endogenous hormone levels [D] . Ling, Chen 2009

机译：一项随机，双盲，安慰剂对照的II期临床试验，用于研究多肽E对内源激素水平的影响
6. Use of clomiphene citrate alone urinary follicle-stimulating hormone alone or both combined sequentially in patients with unexplained subfertility undergoing intrauterine insemination: A randomized trial [O] . Reyhan Ayaz, Mehmet Reşit Aşoglu, Selçuk Ayas 2018

机译：在无法解释的不育症患者接受子宫内授精的患者中单独使用柠檬酸克罗米芬单独刺激尿卵泡激素或同时使用这两种药物：一项随机试验
7. The SUPER study: protocol for a randomised controlled trial comparing follicle-stimulating hormone and clomiphene citrate for ovarian stimulation in intrauterine insemination [O] . Danhof, N. A., van Wely, M., Koks, C. A. M., 2017

机译：SUPER研究：一项在子宫内授精中比较卵泡刺激激素和柠檬酸克罗米芬对卵巢刺激的随机对照试验的方案

Follicle stimulating hormone versus clomiphene citrate in intrauterine insemination for unexplained subfertility: a randomized controlled trial

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