Comments About: Prognostic Significance of Heart Rate and Beta-Blocker Use in Sinus Rhythm in Patients with Heart Failure and Preserved Ejection Fraction

摘要

The article entitled “Prognostic significance of heart rate and beta-blocker use in sinus rhythm in patients with heart failure and preserved ejection fraction” has an interesting conclusion that involves prognostic connotations [1]. Indeed, authors concluded that lower heart rate was associated with lower mortality in the Chinese population included in their study. The analysed population included 330 elderly patients admitted with heart failure diagnosis. As has been largely reported, circulatory failure has nowadays pandemic characteristics [2] and the available treatment in the last stage (cardiac transplant) is a possibility hardly limited by the few number of donors with respect to the long list of potential recipients. This undesirable situation has determined the biomechanical modelization of the cardiovascular system [3] and the investigation of circulatory assist devices effect [4]. The use of the mentioned devices is onerous and limited by the infection, haemorrhagic and thrombotic episodes that occur in a significant number of patients. Therefore, in clinical practice physicians direct their efforts to decrease both, morbidity and mortality through pharmacological interventions [5] and other preventive measures.