The analgesic effect of intraarticular OnabotulinumtoxinA in a female murine model of collagenase induced chronic degenerative monoarthritis

Blanshan Nicole; Mahowald Maren L.; Dorman Christopher; Frizelle Sandra; Krug Hollis E.

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The analgesic effect of intraarticular OnabotulinumtoxinA in a female murine model of collagenase induced chronic degenerative monoarthritis

机译：骨髓炎蛋白在胶原酶诱导的慢性退化单细胞炎雌性鼠模型中的镇痛作用

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Purpose: We previously reported the efficacy of intraarticular (IA) rimabotulinumtoxinB (BoNT/B) in a murine model of chronic degenerative arthritis pain. This study aimed to measure the analgesic effects of onabotulinumtoxinA (BoNT/A) on collagenase induced chronic degenerative arthritis joint pain.

机译：目的：我们之前报道了细胞内（IA）RimaboTulinumtoxinb（Bont / B）在慢性退行性关节炎疼痛的小鼠模型中的疗效。本研究旨在测量OnaboTulinumtoxina（Bont / A）对胶原酶诱导的慢性退行性关节炎关节疼痛的镇痛作用。

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来源
《Toxicon: An International Journal Devoted to the Exchange of Knowledge on the Poisons Derived from Animals, Plants and Microorganisms》 |2019年第2019期|共8页
作者
Blanshan Nicole; Mahowald Maren L.; Dorman Christopher; Frizelle Sandra; Krug Hollis E.;
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作者单位

Vet Affairs Med Ctr Rheumatol Dept Minneapolis MN USA;

Vet Affairs Med Ctr Rheumatol Dept Minneapolis MN USA;

Vet Affairs Med Ctr Rheumatol Dept Minneapolis MN USA;

Vet Affairs Med Ctr Rheumatol Dept Minneapolis MN USA;

Vet Affairs Med Ctr Rheumatol Dept Minneapolis MN USA;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Botox (TM); Osteoarthritis; Mouse; Pain; Neurotoxins;

机译：Botox（TM）;骨关节炎;小鼠;疼痛;神经毒素;

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1. The analgesic effect of intraarticular OnabotulinumtoxinA in a female murine model of collagenase induced chronic degenerative monoarthritis [J] . Blanshan Nicole, Mahowald Maren L., Dorman Christopher, Toxicon: An International Journal Devoted to the Exchange of Knowledge on the Poisons Derived from Animals, Plants and Microorganisms . 2019,第期

机译：骨髓炎蛋白在胶原酶诱导的慢性退化单细胞炎雌性鼠模型中的镇痛作用
2. Intraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis [J] . Takumi Sakamoto, Tsuyoshi Miyazaki, Shuji Watanabe, BMC Musculoskeletal Disorders . 2019,第1期

机译：细胞内注射加工的脂肪痉挛细胞具有抗炎和镇痛作用，但不改善小鼠单碘酸乙酯诱导的骨关节炎的退行性变化
3. Analgesic effects of intra-articular botulinum toxin Type B in a murine model of chronic degenerative knee arthritis pain [J] . Stephanie Anderson, Hollis Krug, Christopher Dorman, Journal of Pain Research . 2010,第5期

机译：B型肉毒杆菌毒素在慢性退行性膝关节炎疼痛小鼠模型中的镇痛作用
4. High Intensity Laser Therapy during chronic degenerative tenosynovitis experimentally induced in chicken broiler [C] . Damiano Fortuna, Giacomo Rossi, Teresa Wanda Bilotta, Laser Florence congresses . 2002

机译：在鸡肉肉鸡实验诱导的慢性退行性腱鞘炎期间高强度激光治疗
5. Qualitative and Quantitative Assessment of Pain in a Naturally-Occurring Model of Feline Chronic Pain (Degenerative Joint Disease) [D] . Gruen, Margaret Elizabeth. 2016

机译：在自然发生的猫慢性疼痛（退化性关节病）模型中对疼痛进行定性和定量评估
6. Intraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis [O] . Takumi Sakamoto, Tsuyoshi Miyazaki, Shuji Watanabe, 2019

机译：关节腔内注射加工过的脂肪抽吸物具有抗炎和镇痛作用但不能改善鼠单碘乙酸盐诱发的骨关节炎的退行性改变
7. Analgesic effects of intra-articular botulinum toxin Type B in a murine model of chronic degenerative knee arthritis pain [O] . Anderson, Stephanie, Krug, Hollis, Dorman, Christopher, 2010

机译：B型肉毒杆菌毒素在慢性退行性膝关节炎疼痛小鼠模型中的镇痛作用

The analgesic effect of intraarticular OnabotulinumtoxinA in a female murine model of collagenase induced chronic degenerative monoarthritis

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